摘要
目的探讨妇科恶性肿瘤患者术后下肢深静脉血栓形成(DVT)的危险因素。方法回顾性分析2018年1月至2020年10月首都医科大学附属北京潞河医院手术治疗的246例妇科恶性肿瘤患者的临床资料,根据其术后是否发生下肢DVT分为DVT组和对照组。分析妇科恶性肿瘤患者术后发生下肢DVT的危险因素。结果246例患者中术后发生下肢DVT 35例。两组年龄、术中出血量、术后凝血酶原时间(PT)、术前及术后D二聚体(D-D)比较,差异有统计学意义(P<0.05)。年龄(OR=1.051)、术后PT(OR=0.657)、术后D-D(OR=1.419)是妇科恶性肿瘤患者发生术后下肢DVT的独立影响因素(P<0.05)。结论妇科恶性肿瘤患者发生术后下肢DVT的危险因素有年龄、术后PT、术后D-D,在临床工作中应密切关注,并采取积极有效的预防措施减少下肢DVT的发生。
Objective To analyze the risk factors of postoperative lower extremity deep venous thrombosis(DVT)in gynecological malignancy patients.Methods Clinical data of 246 gynecological malignancy patients who treated by operation in Beijing Luhe Hospital,Capital Medical University from January 2018 to October 2020 were retrospectively reviewed.They were divided into DVT group and control group,according to whether they were complicated with lower extremity DVT.The risk factors of postoperative lower extremity DVT in gynecological malignancy patients were analyzed.Results Postoperative DVT of lower extremity occurred in 35 of 246 patients.There were statistically significant differences in age,intraoperative blood loss,postoperative prothrombin time(PT),preoperative,and postoperative D-dimer(D-D)between two groups(P<0.05).Age(OR=1.051),postoperative PT(OR=0.657),and postoperative D-D(OR=1.419)were independent influencing factors for postoperative DVT in patients with gynecological malignancies(P<0.05).Conclusion The risk factors of postoperative DVT in patients with gynecological malignant tumor include age,postoperative PT,and postoperative D-D,which should be paid close attention to in clinical work,and active and effective preventive measures should be taken to reduce the occurrence of lower extremity DVT.
作者
崔秀平
李晓娟
周勤
桑翠琴
CUI Xiuping;LI Xiaojuan;ZHOU Qin;SANG Cuiqin(Department of Gynecology,Beijing Luhe Hospital,Capital Medical University,Beijing101149,China;Department of Obstetrics and Gynecology,Beijing Chaoyang Hospital,Capital Medical University,Beijing100020,China)
出处
《中国医药导报》
CAS
2023年第11期84-88,共5页
China Medical Herald
基金
首都卫生发展科研专项(重点攻关)项目(首发2018-1-1061)
北京市通州卫生发展科研专项项目(TFZXPT-20180106)。
