摘要
目的探讨普瑞巴林治疗糖尿病痛性周围神经病变的疗效。方法选取2021年1月—2022年1月期间巨野县人民医院收治的60例糖尿病痛性周围神经病变患者为研究对象,入院后以电脑随机法分为对照组(n=30,予常规控糖+依帕司他治疗)和研究组(n=30,予常规控糖+依帕司他+普瑞巴林治疗),对比两组治疗有效率、疼痛评分、不良反应发生率。结果研究组治疗有效率高于对照组,差异有统计学意义(P<0.05);研究组疼痛评分、频率、最长持续时间优于对照组,差异有统计学意义(P<0.05)。结论普瑞巴林对治疗糖尿病痛性周围神经病变具有临床优势,可显著减少疼痛程度、频率及最长持续时间,同时治疗过程中不会影响运动及感觉神经传导速度的恢复及安全性。
Objective To investigate the efficacy of pregabalin in the treatment of diabetic painful peripheral neuropathy.Methods Sixty patients with painful peripheral neuropathy caused by diabetes admitted to Juye County People's Hospital from January 2021 to January 2022 were selected as research objects.After admission,they were randomly divided into the control group(n=30,treated with conventional glucose control+epalrestat)and the study group(n=30,treated with conventional glucose control+epalrestat+pregabalin)by computer.The treatment efficiency,pain score,and incidence of adverse reactions of the two groups were compared.Results The effective rate of treatment in the study group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).The pain score,frequency and longest duration of the study group were better than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Pregabalin has clinical advantages in the treatment of diabetic painful peripheral neuropathy,which can significantly reduce the severity,frequency and longest duration of pain.At the same time,it does not affect the recovery and safety of motor and sensory nerve conduction velocity during the treatment.
作者
原艺萌
许继坤
祝海英
YUAN Yimeng;XU Jikun;ZHU Haiying(Department of Endocrinology,Juye County People's Hospital of Heze,Heze,Shandong Province,274900 China)
出处
《糖尿病新世界》
2023年第1期134-136,140,共4页
Diabetes New World Magazine
