摘要
目的:分析单侧附件切除手术治疗早期卵巢癌患者临床疗效及对患者术后月经、生育功能影响。方法:收集本院2016年12月-2020年12月收治的101例卵巢癌患者临床资料,根据不同治疗方案分为单侧组(n=45,单侧附件切除术)、单双侧组(n=31,单/双侧卵巢肿物剥除)、单双侧+分期手术组(n=25,单/双侧卵巢肿物剥除+分期手术)。比较3组围手术期指标、焦虑、抑郁及术后1年月经及妊娠情况。结果:单侧组手术时间、术中出血量均低于另外两组(P<0.05)。单双侧组6例复发,给予肿瘤细胞减灭术治疗后,彻底丧失生育能力。术后1年内,单侧组、单双侧组月经正常占比(84.4%、80.5%)高于单双侧+分期手术组(56.0%),妊娠成功率单侧组(73.3%)>单双侧+分期手术组(36.0%)>单双侧组(6.5%)(均P<0.05)。3组生育婴儿均发育正常,未见畸形。术后3组焦虑自评表(SAS)、抑郁自评表(SDS)评分均较术前降低,且单侧组低于另外两组(P<0.05)。结论:采用单侧附件切除手术治疗早期卵巢癌患者疗效显著,可改善患者月经情况、心理状况,有效保留生育功能。
Objective:To analyze the therapeutic effect of unilateral adnexectomy for treating patients with early ovarian cancer,and to study its influence on the menstruation and fertility function of these patients.Methods:The clinical da-ta of 101 patients with early ovarian cancer from December 2016 to December 2020 were collected.According to differ-ent treatment,these patients were divided into group A(45 patients with unilateral adnexectomy)and group B(31 pa-tients with unilateral/bilateral ovarian mass removal),and group C(25 patients with unilateral/bilateral ovarian mass removal combined with staging surgery).The perioperative indicators,the status of anxiety and depression,and the postoperative menstruation and pregnancy situation within 1 year of the patients were compared among the three groups.Results:The operative time and the intraoperative blood loss of the patients in group A were significantly low-er than those of the patients in the other two groups(P<0.05).There were 6 patients with the recurrence of ovarian cancer in group B,and then they lost their fertility completely after tumor cell reduction therapy.Within 1 year after surgery,the proportion of normal menstruation of the patients in group A(84.4%)and in group B(80.5%)was sig-nificantly higher than that(56.0%)of the patients in group C.The success rate of pregnancy of the patients in group A(73.3%),in group C(36.0%),and in group B(6.5%)had decreased gradually(all P<0.05).All the babies in the three groups developed normally and no any baby with malformations was observed.The scores of SAS and SDS of the patients in the three groups after surgery had decreased significantly,and which of the patients in group A were signifi-cantly lower than those of the patients in the other two groups(P<0.05).Conclusion:Unilateral adnexectomy for treating the patients with early ovarian cancer has outstanding effective,which can improve their menstrual and Psy-chological condition,and can effectively preserve their reproductive function.
作者
谢桃红
陈体平
陈蓉
赵磊
冯小兵
XIE Taohong;CHEN Tiping;CHEN Rong;ZHAO Lei;FENG Xiaobing(Luzhou People's Hospital,Luzhou,Sichuan Province,646000)
出处
《中国计划生育学杂志》
2023年第4期869-872,共4页
Chinese Journal of Family Planning
关键词
卵巢癌
单侧附件切除术
临床疗效
生育功能
心理
月经
Ovarian cancer
Unilateral adnexectomy
Clinical efficacy
Fertility function
Psychology
Menstruation
