摘要
手术切缘是肝癌外科治疗的基本问题,但是迄今为止这个具有重要临床意义的问题仍然存在诸多争议。多数研究提出理论上残肝体积足够时,宽切缘能让患者获得更好的生存获益。然而,也有部分研究发现切缘宽度对单发肝细胞癌患者预后无显著影响。因此,针对肝细胞癌最佳手术切缘宽度的争议,本文重点关注切缘宽度在个体因素方面对单发肝细胞癌患者根治性肝切除术后生存获益的影响。
Surgical margin is a fundamental issue in the surgical management of hepatocellular carcinoma,but this clinically important issue remains controversial to date.Most studies have suggested that wide margins theoretically provide a better survival benefit when the volume of the remnant liver is adequate,however,some studies have also found no difference in the prognostic impact of margin width in patients with single hepatocellular carcinoma.Therefore,the optimal surgical margin width for hepatocellular carcinoma remains controversial.In this article,we focus on the impact of cutting margin width in terms of Individualized factors on the survival benefit after radical hepatectomy in patients with solitary hepatocellular carcinoma.
作者
朱晓颖
王粟
杨世忠
Zhu Xiaoying;Wang Su;Yang Shizhong(Hepatopancreatobiliary Surgery,Affiliated Hospital of Qinghai University,Xining 810000,Qinghai,China;Hepatobiliary and Pancreatic Center,Tsinghua Chang Gung Hospital,Institute of Precision Medicine,School of Clinical Medicine,Beijing 102218,China)
出处
《中国医学前沿杂志（电子版）》
CSCD
2023年第4期71-75,共5页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
基金
清华大学精准医学科研项目(2022ZLA007)
国家自然科学基金重大项目(82090052)。
关键词
手术切缘
肝切除
肝细胞癌
预后
Surgical margin
Liver resection
Hepatocellular carcinoma
Prognosis
