摘要
目的探析局部晚期宫颈癌应用三维后装腔内放疗临床效果及对放射性直肠炎、膀胱炎发生的影响。方法随机选取2019年2月-2020年5月于深圳市人民医院就诊的实施三维后装腔内放疗的40例晚期宫颈癌患者作为观察组,回顾性分析2012年2月-2013年5月于本院就诊的实施二维后装腔内放疗的40例晚期宫颈癌患者的临床资料,作为对照组。对比两组临床疗效及不良反应评价。结果观察组治疗有效率(PP)(75.00%)明显高于对照组PP(52.50%),差异有统计学意义(χ^(2)=4.381,P<0.05);两组均无4级放射性膀胱炎发生,且观察组放射性膀胱炎率(7.50%)明显低于对照组(42.50%),差异有统计学意义(χ^(2)=13.067,P<0.05)。观察组放射性直肠炎发生率(32.50%)明显低于对照组(57.50%),差异有统计学意义(χ^(2)=5.051,P<0.05)。结论三维后装腔内放疗应用于局部晚期宫颈癌临床效果显著,可有效降低放射性直肠炎、膀胱炎发生率。
Objective To explore the clinical effect of applying three-dimensional post-mounted intracavitary radiotherapy for locally advanced cervical cancer and the effect on the occurrence of radiation proctitis and cystitis.Meth⁃ods 40 patients with advanced cervical cancer who attended Shenzhen People's Hospital from February 2019 to May 2020 were randomly selected,as the observation group implemented with three-dimensional post-mounted intracavitary radiotherapy implemented,and the data of the 40 patients with advanced cervical cancer attending the hospital from February 2012 to May 2013 were retrospectively analyzed as the control group,implemented with twodimensional post-mounted intracavitary radiotherapy.The clinical efficacy and evaluation of adverse reactions of the two groups were compared.Results The treatment efficiency(PP)of the observation group(75.00%)was significantly higher than that of the control group PP(52.50%),and the difference was statistically significant(χ^(2)=4.381,P<0.05).No grade 4 radiation cystitis occurred in two groups,and the rate of radiation cystitis(7.50%)in the observation group was significantly lower than that in the control group(42.50%),and the difference was statistically significant(χ^(2)=13.067,P<0.05).The rate of radiation proctitis in the observation group(32.50%)was significantly lower than that in the control group(57.50%),and the difference was statistically significant(χ^(2)=5.051,P<0.05).Conclusion Threedimensional post-mounted intracavitary radiotherapy applied to locally advanced cervical cancer is clinically effective and can effectively reduce the incidence of radiation proctitis and cystitis.
作者
方敏捷
周亚燕
闫茂生
全任翠
杨红丽
刘景文
李先明
FANG Minjie;ZHOU Yayan;YAN Maosheng;QUAN Rencui;YANG Hongli;LIU Jingwen;LI Xianming(Department of Oncology Radiotherapy,Shenzhen People's Hospital,Shenzhen,Guangdong Province,518000 China)
出处
《中外医疗》
2022年第33期44-47,共4页
China & Foreign Medical Treatment
基金
深圳市卫生计生系统科研项目(SZFZ2018018)。
关键词
三维后装腔内放疗
局部晚期宫颈癌
临床效果
放射性直肠炎
放射性膀胱炎
Three-dimensional post-mounted intracavitary radiotherapy
Locally advanced cervical cancer
Clinical effect
Radiation proctitis
Radiation cystitis
