期刊文献+

基于数据挖掘近10年现代医家治疗良性前列腺增生的执方用药规律

The Prescription Medication Rules of Modern Doctors in the Treatment of Benign Prostatic Hyperplasia in Recent 10 Years Based on Data Mining
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摘要 目的基于中医传承辅助平台(V2.5)软件,分析近十年中国知网(CNKI)中现代医家运用中医药治疗良性前列腺增生(EPH)的用药规律和治疗思路。方法收集并筛选CNKI中公开发表的运用中医药治疗EPH的文献,设定时间2010年1月—2020年1月,将所得中医处方全部录入中医传承辅助平台(V2.5)软件,运用该系统中的数据分析方法,对药物进行频次统计、归经统计、处方规律分析、聚类新处方分析。结果筛选出符合条件文献70篇,其中共获得77首处方,对其进行数据分析,发现22味中药被高频使用,频次前5位的分别是黄英、牛膝、茯苓、车前子、当归;通过聚类分析得出核心药物组合有4组,治疗EPH新处方2首。结论中医治疗EPH使用的药物中,大多为补益药、活血药、利尿药,着重调理肝肾脾经,起到补气温阳、活血化瘀、利尿通淋的功效,提示医家临证治疗本病注重分清虚实两端,通利结合,消补共济,为今后中医辨治EPH提供依据,另挖掘出2首BPH新处方,其组方配伍体现中医整体特色。 Objective To analyze the medication regularity and treament ideas of modem physicians in China National Knowledge Infrastructure(CNKI)database for the treatment of benign prostatic hyperplasia(BPH)using traditional Chinese medicine(TCM)in the past ten years.Methods We collected and selected the literatures of treating BPH from January 2010 to January 2020 from CNKI database,and imported the all acupoints to TCM inheritance auxiliary system(V2.5).To analyze the frequency of four properties,five tastes,acupoints,therapeutic targets and new scription by Using the data analysis method in the system.Results A total of 70 eligible literatures were screened,including 77 prescriptions.Through analysis,totally 22 frequently uesd herbs were found,and the top five were Astragali Radix,Achyranthis Bidentatae Radix,Poria,Plantaginis Semen and Angelicae Sinensis Radbc Totally 4 core combination were mined by association rules,and two new prescriptions of treating BPH were mined through the cluster analysis from the database.Conclusion The medicine is mainly based on tonic,blood-activating and clearing damp and promoting diuresis medicine during all herbs of treating BPH.It focuses on the regulation of liver,kidney and spleen meridians.Invigorating Qi and warm Yang,blood-activating and stasis-removing and clearing damp and promoting diuresis are used as the main therapeutic methods.Clinical treatment focuses on the distinction between deficiency and excess of both ends,the combination of tongli,eliminate and supplement together to provide a basis for future treatment of BPH.
作者 吴丽通 车祖钊 陈树超 李其信 陈颖雯 张泽政 游旭军 傅伟 WU Li-tong;CHE Zu-zhao;CHEN Shu-chao;LI Qi-xin;CHEN Ying-wen;ZHANG Ze-zheng;YOU Xu-jun;FU Wei(Seventh Clinic School of Medicine,Guangzhou University of Traditional Chinese Medicine,Shenzhen Guangdong 518133,China;Graduate School of Hunan University of Chinese Medicine,Changsha Hunan 410208,China)
出处 《中华养生保健》 2023年第9期18-22,共5页 CHINESE HEALTH CARE
基金 广东省中医药局课题(20221339) 深圳市科技计划项目(JCYJ20180302144752020) 广东省基层老中医药专家传承工作室建设项目[粤中医办函(2020)1号] 宝安区医疗卫生基础研究项目(2020JD537)。
关键词 良性前列腺增生 数据挖掘 中医传承辅助系统 用药规律 关联规则 benign prostatic hyperplasia data mining TCM inheritance auxiliary system medication rule association rules
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