摘要
目的观察新加玉屏风汤联合维生素D治疗早期维生素D缺乏性佝偻病的临床疗效。方法选取武威市凉州区中西医结合医院2019年8月-2020年7月儿科门诊就诊的67例维生素D缺乏性佝偻病患儿,按照随机数字表法分为对照组(n=33)和治疗组(n=34)。对照组给予口服维生素D滴剂,治疗组在对照组基础上服用新加玉屏风汤颗粒剂,治疗3个月后,比较2组临床疗效及血清25羟基维生素D[25-(OH)D]、NBAP水平。结果治疗前,2组血清25-(OH)D、NBAP水平差异不明显(P>0.05);治疗3个月后,治疗组血清骨源性碱性磷酸酶(NBAP)水平比对照组低,25-(OH)D水平比对照组高(P<0.05)。治疗组治疗总有效率为96.67%,高于对照组的80.00%(P<0.05)。结论新加玉屏风汤联合维生素D治疗早期维生素D缺乏性佝偻病疗效确切,而且可以促进血清25-(OH)D、NBAP水平的改善,值得推广。
Objective To observe the clinical effect of Xinjia Yupingfeng decoction combined with vitamin D in the treatment of early vitamin D deficiency rickets.Methods 67 children with vitamin D deficiency rickets treated in the pediatric outpatient department of Liangzhou District Hospital of integrated traditional Chinese and Western medicine in Wuwei City from August 2019 to July 2020 were randomly divided into control group(n=33)and treatment group(n=34).The control group was given oral vitamin D drops,and the treatment group was given Xinjia Yupingfeng Decoction granules on the basis of the control group.After 3 months of treatment,the clinical efficacy and serum 25-(OH)D Changes in NBAP levels.Results Before treatment,there was no significant difference in serum 25-(OH)D and NBAP levels between the two groups(P>0.05);After 3 months of treatment,the serum NBAP level in the treatment group was lower than that in the control group,and the 25-(OH)D level was higher than that in the control group(P<0.05);The total effective rate of the treatment group was 96.67%higher than 80.00%in the control group(P<0.05).Conclusion Xinjia Yupingfeng decoction combined with vitamin D is effective in the treatment of early deficiency rickets,and can promote the improvement of serum 25-(OH)D and NBAP levels,which is worth popularizing.
作者
王晓丽
汪斌
徐天鹏
窦世琼
张宏山
严文娟
Wang Xiaoli;Wang Bin;Xu Tianpeng(The Liangzhou District Integrated Traditional Chinese and Western Medicine Hospital of Wuwei City,Wuwei,Gansu 733000;The Liangzhou Hospital of Wuwei City,Wuwei,Gansu 733000)
出处
《基层医学论坛》
2023年第11期108-110,共3页
The Medical Forum
基金
武威市市列科技计划项目(WW1901105)。
