摘要
目的 探讨CT对肺磨玻璃结节(ground-glass nodule, GGN)肺浸润性腺癌与肺微浸润腺癌的鉴别价值。方法 回顾性分析74例肺浸润性腺癌与83例肺微浸润腺癌患者的临床资料,患者均进行CT检查,表现为GGN,分别将其归为浸润组(n=74,肺浸润腺癌患者)和微浸润组(n=83,肺微浸润腺癌患者),比较2组患者结节直径、形态、CT值、结节类型、分叶征、毛刺征、胸膜凹陷征、空泡征等CT影像特征,选取存在显著差异的变量行二元logistic回归分析,分析CT对GGN肺浸润性腺癌与肺微浸润腺癌的鉴别诊断价值。结果 浸润组患者结节直径、CT值均高于肺微浸润腺癌患者,差异有统计学意义(P<0.05)。2组患者结节类型、结节形态、分叶征、毛刺征等CT影像特征比较,差异有统计学意义(P<0.05),2组患者结节胸膜凹陷征、空泡征比较,差异无统计学意义(P>0.05)。结节直径大、CT值高、混合性磨玻璃结节(mGGN)、不规则形结节、有分叶征、有毛刺征均与肺浸润性腺癌显著相关(P<0.05)。结论 GGN患者的结节直径、CT值、结节类型、形态、分叶征、毛刺征等CT影像特征,均对肺浸润性腺癌与微浸润腺癌有一定鉴别价值,能为临床诊断及治疗提供有力依据。
Objective To explore the value of CT in differentiating pulmonary invasive adenocarcinoma from microinvasive adenocarcinoma in pulmonary ground glass nodules.Methods The clinical data of 74 patients with pulmonary invasive adenocarcinoma and 83 patients with microinvasive adenocarcinoma were retrospective analyzed.All patients underwent CT examination and showed GGN.CT imaging features such as nodule diameter,morphology,CT value,nodule type,lobar sign,burr sign,pleural depression sign and vacuole sign were compared between the two groups,and the variables with significant differences were selected for binary logistic regression analysis to analyze the differential diagnostic value of CT for GGN pulmonary invasive adenocarcinoma and microinvasive adenocarcinoma.Results The nodule diameter and CT value in the invasive group were higher than those in the microinvasive group(P<0.05).There were statistically significant differences in CT imaging features such as nodule type,nodule morphology,lobar sign and burr sign compared between the two groups(P<0.05).There was no significant difference in pleural indentation and vacuole sign between the two groups(P>0.05).Large nodule diameter,high CT values,mixed ground glass nodules(mGGN),irregular shaped nodules,presence of lobar signs,and presence of burr signs were all significantly associated with pulmonary invasive adenocarcinoma(P<0.05).Conclusion The nodule diameter,CT value,nodule type,morphology,lobar sign,burr sign and other CT imaging features of GGN patients are all valuable in differentiating pulmonary invasive adenocarcinoma from microinvasive adenocarcinoma,which can provide a strong basis for clinical diagnosis and treatment.
作者
刘永震
董可
狄楠
LIU Yongzhen;DONG Ke;DI Nan(Department of Medical Imaging,the Sixth People’s Hospital of Shangqiu,Shangqiu Henan 476000,China)
出处
《河南医学高等专科学校学报》
2023年第2期132-135,共4页
Journal of Henan Medical College
关键词
肺磨玻璃结节
CT
肺浸润性腺癌
肺微浸润腺癌
ground glass nodules
CT
pulmonary invasive adenocarcinoma
microinvasive adenocar-cinoma
