摘要
目的研究内镜黏膜下剥离术治疗消化道黏膜下肿瘤的临床效果和安全性。方法选择2020年1月至2021年1月新乡医学院第一附属医院收治的60例患有消化道黏膜下肿瘤的患者作为研究对象,根据治疗方法分为两组,各30例。其中,对照组患者接受常规胸腔镜/腹腔镜治疗;研究组患者接受内镜黏膜下剥离术治疗。对治疗后两组患者的手术情况、术后病理情况、术后不良反应、瘤体完整切除率与1 a内复发率进行比较。结果经过不同的手术方式治疗后,研究组的手术时间、手术中总出血量、术后进食时间与住院时间均低于对照组(P<0.05)。研究组肿瘤直径0.7~2.6(1.71±0.37)cm,对照组肿瘤直径0.6~2.5(1.72±0.32)cm,两组之间差异无统计学意义(P>0.05)。研究组病理危险度分级:极低危28例,低危1例,高危1例。对照组病理危险度分级:极低危26例,低危3例,高危1例。研究组术后不良反应的总发生率为6.67%,与对照组(33.33%)差异有统计学意义(P<0.05)。经过不同治疗后,两组患者的瘤体完整切除率与术后1 a内的复发率差异无统计学意义(P>0.05)。结论内镜黏膜下剥离术治疗消化道黏膜下肿瘤的临床效果较好,出血量较低,患者术后不良反应较低,值得推广。
Objective To investigate the clinical efficacy and safety of endoscopic submucosal dissection in the treatment of gastrointestinal submucosal tumor.Methods A total of 60 patients with gastrointestinal submucosal tumor admitted to First Affiliated to Xinxiang Medical College Hospital from January 2020 to January 2021 were selected as the research objects and divided into two groups according to the treatment method,with 30 cases each.Patients in the control group received with thoracoscopy/laparoscopy treatment.Patients in the study group received with endoscopic submucosal dissection.The operation,postoperative pathology,postoperative adverse reactions,tumor resection rate and recurrence rate within one year were compared between the two groups after treatment.Results The operation time,intraoperative blood loss,postoperative feeding time and hospital stay in the study group were lower than those in the control group(P<0.05).The tumor diameter of the study group was 0.7-2.6(1.71±0.37)cm,and that of the control group was 0.6-2.5(1.72±0.32)cm,and there was no significant difference between the two groups(P>0.05).The pathological risk classification of the study group included 28 cases of very low risk,1 case of low risk,and 1 case of high risk.In the control group,26 cases were very low risk,3 cases were low risk,and 1 case was high risk.The total incidence of postoperative adverse reactions in the study group was 6.67%,which was different from 33.33%in the control group(P<0.05).After different treatments,there was no significant difference between the two groups in the tumor complete resection rate and the recurrence rate one year after surgery(P>0.05).Conclusion Endoscopic submucosal dissection for the treatment of submucosal tumor has a good clinical effect,low blood loss,low postoperative adverse reactions,which is worthy of promotion.
作者
杨芳
杨璐
郭晓鹤
孙培胜
YANG Fang;YANG Lu;GUO Xiaohe;SUN Peisheng(Department of Gastroenterology,the First Affiliated Hospital of Xinxiang Medical College,Xinxiang 453100,China;Department of Gastrointestinal Surgery,the First Affiliated Hospital of Xinxiang Medical College,Xinxiang 453100,China)
出处
《河南医学研究》
CAS
2023年第6期1082-1084,共3页
Henan Medical Research
基金
河南省医学科技攻关计划项目(LHGJ20210539)。
关键词
消化道黏膜下肿瘤
内镜黏膜下剥离术
临床疗效
安全性
gastrointestinal submucosal tumor
endoscopic submucosal dissection
clinical curative effect
safety
