摘要
脑血管畸形(CVM)是指脑局部血管数量和结构的非肿瘤性发育异常所导致的疾病。癫痫发作是CVM常见的临床表现,主要存在于脑动静脉畸形和脑海绵状血管瘤两种CVM病理类型中。CVM相关癫痫为患者带来一系列的负担,是CVM临床诊疗中改善患者预后需要考虑的重要因素。现总结CVM相关癫痫的研究进展,对其发生率、发病机制、所导致的脑网络功能连接损伤、相关危险因素、个体化评估、治疗及预后等进行综述,旨在对CVM相关癫痫建立更加全面的认识,从而辅助CVM临床诊疗。
Cerebral vascular malformations(CVM)are non-neoplastic lesions caused by abnormalities in the number and structure of brain vessels.Epileptic seizure is a frequent presenting symptom in patients with CVM,particularly in patients with brain arteriovenous malformations and cavernous malformations.CVMrelated epilepsy brings a series of burdens to patients,which is an essential factor to be considered in achieving a favorable prognosis for CVM.In this paper,we review the research advances in CVM-related epilepsy,including its incidence,pathogenesis,altered brain functional connectivity,risk factors,individualized evaluation,treatment,and prognosis,with the goal of assisting the diagnosis and treatment of CVM.
作者
赵绍智
铁艳梅
Zhao Shaozhi;Tie Yanmei(Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University,National Center for Clinical Medical Research of Neurological Diseases,Beijing 100070,China;Department of Neurosurgery,Brigham and Women's Hospital,Harvard Medical School,Boston 02115,USA)
出处
《神经疾病与精神卫生》
2023年第2期104-110,共7页
Journal of Neuroscience and Mental Health
关键词
脑血管畸形
癫痫
脑动静脉畸形
脑海绵状血管瘤
神经影像
综述
Cerebral vascular malformations
Epilepsy
Arteriovenous malformations
Cerebral cavernous malformations
Neuroimaging
Review
