摘要
目的分析1990—2019年江苏省非霍奇金淋巴瘤疾病负担变化情况,为非霍奇金淋巴瘤的防控提供科学依据。方法利用2019年全球疾病负担数据库江苏省非霍奇金淋巴瘤的发病数、发病率、死亡数、死亡率、伤残调整寿命年(disability adjusted life years,DALYs)、DALYs率,分析1990—2019年江苏省非霍奇金淋巴瘤的性别、年龄分布及其变化趋势。结果2019年江苏省非霍奇金淋巴瘤发病数为7299例,标化发病率为5.92/10万,死亡数为3182例,标化死亡率为2.45/10万,DALYs为85328人年,标化DALYs率为71.79/10万。与1990年相比,各指标均呈上升趋势。不同性别人群非霍奇金淋巴瘤年龄别发病率、死亡率和DALYs率均随年龄的增长而升高,但男性发病率、死亡率和DALYs率高于女性,差异有统计学意义(P<0.05)。结论1990—2019年江苏省非霍奇金淋巴瘤疾病负担呈加重的趋势,男性和高龄人群是其疾病负担的高危人群,应针对非霍奇金淋巴瘤制定综合防控措施,减轻患者疾病负担。
Objective To analyze the changes in disease burden of non-Hodgkin’s lymphoma in Jiangsu Province from 1990 to 2019,and to provide a scientific basis for prevention and control of non-Hodgkin’s lymphoma.Methods We analyzed the gender,age distribution and changing trends of non-Hodgkin’s lymphoma in Jiangsu Province during 1990-2019 based on the case number,incidence,mortality,disability-adjusted life years(DALYs),and DALYs rate of non-Hodgkin’s lymphoma in Jiangsu Province extracted from the database of the Global Burden of Disease Study 2019.Results In 2019,the number of non-Hodgkin’s lymphoma cases in Jiangsu Province was 7,299,and the standardized incidence rate was 5.92/100,000.The number of deaths was 3,182,and the standardized mortality rate 2.45/100,000.The DALYs was 85,328 person-years,and the standardized DALYs rate 71.79/100,000.Compared with those in 1990,all indicators showed an upward trend.The age-specific morbidity,mortality and DALYs rate of non-Hodgkin’s lymphoma in different gender populations all increased with age,but the morbidity,mortality and DALYs rate were higher in males than in females,showing statistically significant differences(P<0.05).Conclusion The disease burden of non-Hodgkin’s lymphoma in Jiangsu Province from 1990 to 2019 showed an increasing trend,and males and the elderly were the high-risk groups of its disease burden.Comprehensive prevention and control measures against non-Hodgkin’s lymphoma should be formulated to reduce disease burden of the patients.
作者
刘付东
李现鹏
许晓庆
俞浩
罗鹏飞
周金意
LIU Fu-dong;LI Xian-peng;XU Xiao-qing;YU Hao;LUO Peng-fei;ZHOU Jin-yi(Yancheng Municipal Center for Disease Control and Prevention,Yancheng,Jiangsu 224002,China;Fushan District Center for Disease Control and Prevention,Yantai,Shandong 265500,China;Jiangsu Provincial Center for Disease Control and Prevention,Nanjing,Jiangsu 210000,China)
出处
《实用预防医学》
CAS
2023年第3期284-287,共4页
Practical Preventive Medicine
基金
江苏省卫生计生委医学科研课题(H2017017)
盐城市医学科技发展计划项目(YK2021033)。
关键词
非霍奇金淋巴瘤
疾病负担
伤残调整寿命年
non-Hodgkin’s lymphoma
disease burden
disability-adjusted life years
