摘要
目的:探讨以时机理论为基础的药学服务干预对慢性阻塞性肺疾病(COPD)患者治疗效果的影响。方法:2021年1月—2022年6月,选取徐州医科大学附属第三医院门诊收治的118例COPD患者,按照随机原则分为药学组与常规组,各59例。常规组实施常规用药指导,药学组实施以时机理论为基础的药学服务干预,两组均干预3个月。比较两组干预前及干预3个月后的用药情况、治疗效果及生活质量。结果:干预3个月后,药学组的Morisky用药依从性问卷(MMAS-8)评分、药物素养评分、用力肺活量(FVC)、最大通气量(MVV)、第1秒用力呼气容积(FEV1)显著高于常规组,临床慢阻肺问卷(CCQ)评分显著低于常规组,差异有统计学意义(P<0.05)。干预3个月后,药学组药品不良事件(ADE)发生率低于常规组,差异有统计学意义(P<0.05)。结论:以时机理论为基础,对COPD患者实施药学服务干预,可提高其药物素养及服药依从性,促进肺功能改善,并可减少ADE发生,提高患者的生活质量。
Objective:To explore the effect of pharmaceutical care intervention based on opportunity theory in the treatment of patients with chronic obstructive pulmonary disease(COPD).Method:A total of 118 patients with COPD who admitted to the outpatient department of the Third Affiliated Hospital of Xuzhou Medical University from January 2021 to June 2022 were divided into pharmaceutical group and conventional group according to the principle of randomization,with 59 cases in each group.The conventional group was given routine medication guidance,and the pharmaceutical group was given pharmaceutical service intervention based on opportunity theory,two groups were intervened for 3 months.The drug use,treatment effect and quality of life of the two groups were compared before and after 3 months of intervention.Result:After 3 months of intervention,the scores of Morisky Medication Adherence Scale 8-item(MMAS-8),drug literacy score,forced vital capacity(FVC),maximum ventilation volume(MVV),forced expiratory volume in the first second(FEV1)in the pharmaceutical group were significantly higher than those in the conventional group,and the scores of clinical COPD questionnaire(CCQ)were significantly lower than those in the conventional group,the differences were statistically significant(P<0.05).After 3 months of intervention,the incidence of adverse drug events(ADE)in the pharmaceutical group was lower than that in the conventional group,the difference was statistically significant(P<0.05).Conclusion:Based on opportunity theory,pharmaceutical care intervention for COPD patients can improve their drug literacy and drug compliance,promote the improvement of pulmonary function,reduce the occurrence of ADE,and improve the quality of life of patients.
作者
胡媛媛
寇智斌
HU Yuanyuan;KOU Zhibin(The Third Affiliated Hospital of Xuzhou Medical University,Xuzhou 221000,China)
出处
《中外医学研究》
2023年第9期110-114,共5页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
慢性阻塞性肺疾病
时机理论
药学服务
用药依从性
药物素养
肺功能
Chronic obstructive pulmonary disease
Timing theory
Pharmaceutical services
Drug compliance
Drug literacy
Pulmonary function
