摘要
肿瘤相关性失眠(CRI)是在肿瘤发生发展及抗肿瘤过程中常见症状之一,但常常被肿瘤患者及医生所忽视,逐渐成为慢性失眠,严重影响患者生存质量,影响抗肿瘤治疗效果。根据失眠与“躁狂越”相似的特征表现,基于《黄帝内经》“诸躁狂越,皆属于火”,探讨从火认识CRI:生理之火维系、保证睡眠发生及正常运行,而基于肿瘤病机及抗肿瘤不良反应而产生的病理之火扰乱心神,导致失眠发生。从恶性肿瘤分期不同,探讨CRI以实火及虚火为不同病因,分别采取升降气机以助清透实火、滋阴潜阳以助虚火下潜对CRI进行辨证论治。
Cancer related insomnia(CRI)is one of the common symptoms in the process of tumor development and anti-tumor treatment.However,CRI is often ignored by patients with tumor and doctors and gradually becomes chronic insomnia.It seriously affects the life quality of patients and the effect of anti-tumor treatment.According to the similar manifestation of insomnia and“restlessness and mania”,based on the“all kinds of diseases with restlessness and mania are exclusively caused by fire”in Huangdi’s Internal Classic,CRI was studied from fire.The physiological fire maintains and ensures the occurrence and normal function of sleep.The pathological fire by tumor pathogenesis and side effects of anti-tumor treatment disturbs the mind and leads to insomnia.According to different stages of malignant tumor,CRI can be caused by excessive fire and deficient fire.Therefore,CRI should be treated according to syndrome differentiation from two aspects:lifting and lowering qi movement to clear excessive fire,and nourishing yin and subduing yang to subdue deficient fire.
作者
朱广辉
李杰
ZHU Guanghui;LI Jie(Oncology Department,Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Graduate School,Beijing University of Chinese Medicine,Beijing 100029,China)
出处
《山东中医杂志》
2023年第4期313-317,共5页
Shandong Journal of Traditional Chinese Medicine
基金
国家中医药管理局科研基金项目(编号:JDZX2105245)
北京市科技计划重大基金项目(编号:D1611100005116004)。
关键词
失眠
肿瘤
生理之火
病理之火
升降气机
滋阴潜阳
insomnia
tumor
physiological fire
patho-logical fire
lifting and lowering qi movement
nouri-shing yin and subduing yang
