摘要
目的建立一套规范化、信息化的用于保存、管理、查询和统计生物样本及其临床数据的信息化管理系统,有利于提高生物样本及其信息的利用率。方法在保障生物样本库运营环境和样本数据安全的前提下,创建一种基于数据库的数据逻辑关系模型,应用于信息管理系统管理和分析中心入组生物样本库患者的生物样本及其配套临床信息。结果为保证随访队列的建立,中心生物样本库持续的采集住院和门诊患者的生物样本和配套的临床信息。2014年12月年至今,共保存来自住院、门诊和科研的生物样本超过27万余份。利用该模型优化的信息管理系统高效的完成了生物样本库基本工作;同时,实现了样本源多种信息的联合查询和批量查询功能,并以报表格式进行相互转换和统计学分析。结论中心信息管理系统符合医院级样本库的建设管理模式,优化的信息管理系统满足了样本库日常工作和研究人员多元的科学需求,为精准医疗的发展提供了便利的平台和丰富的资源。
Objective To establish a standardized information management system(IMS)for preserving,managing,querying,and performing statistics on biospecimens and their clinical data,which is conducive to improving the utilization of biobank.Methods Under the premise of ensuring operating environment and data security,a database-based data logic relationship model is created and applied to the IMS to manage and analyze biospecimens and their supporting clinical information of patients enrolled in the biobank of our center.Results To ensure the establishment of the follow-up cohort,biospecimens and clinical information of inpatients and outpatients were continuously collected in the biobank of our center.Since December 2014,more than 270000 biospecimens from inpatient,outpatient,and scientific research have been preserved.The IMS optimized by this model efficiently completes the basic work of the biobank.At the same time,the data can be queried jointly and in batches,and then converted into a report format for statistical analysis.Conclusions The IMS of our center is suitable for application and popularization as a construction and management model for the hospital-level biobank,which meets the daily work of the biobank and diverse research needs,and provides a convenient platform and rich resources for the development of precision medicine.
作者
张骐麒
宁晓艳
黄慧
刘春艳
孙雪滢
甄乐
王志东
蒲春文
Zhang Qiqi;Ning Xiaoyan;Huang Hui;Liu Chunyan;Sun Xueying;Zhen Le;Wang Zhidong;Pu Chunwen(Department of Biobank,Dalian Public Health Clinical Center,Dalian 116031,Liaoning Province,China;Ministry of Science and Education,Dalian Public Health Clinical Center,Dalian 116031,Liaoning Province,China;Information Department,Dalian Public Health Clinical Center,Dalian 116031,Liaoning Province,China;Department of Pathology,Dalian Public Health Clinical Center,Dalian 116031,Liaoning Province,China)
出处
《中华医学科研管理杂志》
2023年第1期62-66,共5页
Chinese Journal of Medical Science Research Management
基金
大连市科技创新基金项目(2021JJ13SN71)
辽宁省自然科学基金项目(20180550784)。
关键词
信息化管理系统
生物样本
联合查询
自定义
Information management system(IMS)
Biospecimens
Conjunctive query
User-defined
