摘要
炎症性肠病(IBD)主要包括克罗恩病和溃疡性结肠炎,是一种慢性非特异性肠道炎性疾病。精准诊疗是对不同亚型和病程阶段的患者,采取特异性的治疗措施从而达到更好的预后,对IBD的诊断和治疗具有重要意义。共聚焦激光内镜(CLE)是一种内镜中进行小视野成像的技术,可以达到实时的黏膜成像和体内组织学检查的效果,在IBD的诊断和鉴别诊断、肠道炎症程度评估、疾病复发预测和异型增生监测中发挥独特作用。本文就上述要点总结CLE在IBD精准诊疗中的应用。
Inflammatory bowel disease,mainly including Crohn′s disease and ulcerative colitis,is a chronic non-specific intestinal inflammatory disease.The precision diagnosis and treatment is to take specific treatment measures for patients with different subtypes and stages of disease to achieve better prognosis,and is important for the diagnosis and treatment of IBD.Confocal laser endomicroscopy(CLE)is a small field imaging technology of endoscope,leading to real-time visualization of mucosal abnormalities and effect of histological examination in vivo.CLE plays unique role in diagnosis and differential diagnosis of IBD,evaluation of inflammation grading,prediction of relapse and monitoring of mucosal dysplasia.This article summarizes the application of CLE in the precision diagnosis and treatment of IBD.
作者
高维通
顾于蓓
邹多武
Gao Weitong;Gu Yubei;Zou Duowu(Department of Gastroenterology,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China)
出处
《中华炎性肠病杂志（中英文）》
2023年第1期13-16,共4页
Chinese Journal of Inflammatory Bowel Diseases
基金
国家自然科学基金(82000494、82170559)
上海市卫生健康委员会卫生行业临床研究专项基金(202040110)。
关键词
炎症性肠病
共聚焦激光内镜
精准诊疗
异型增生
Inflammatory bowel disease
Confocal laser endomicroscopy
Precision diagnosis and treatment
Dysplasia
