摘要
目的:比较射频消融术对不同左心室射血分数(LVEF)心力衰竭(简称心衰)合并持续性心房颤动(简称房颤)的临床效果。方法:选取射血分数中间值心衰(HFmrEF,LVEF 40%~49%)25例和射血分数降低的心衰(HFrEF,LVEF<40%)30例,给予射频消融术治疗,术后进行房颤药物管理3个月。术后6个月随访心脏超声数据,记录两组手术前后LVEF、左房直径(LAD)、左室收缩末期容积(LVESV)、左室舒张末期容积(LVEDV)、肺动脉压、二尖瓣反流(MR)、三尖瓣反流(TR)情况。结果:两组术后LVEF增加,LAD、LVESV、LVEDV、肺动脉压降低(P<0.05),术前术后差值比较,差异无统计学意义(P>0.05)。两组术后MR及TR改善情况比较,差异无统计学意义(P>0.05)。结论:射频消融术可改善不同LVEF心衰合并持续性房颤患者的临床指标,HFrEF和HFmrEF患者之间改善程度未见明显差异。
Aim:To compare the clinical efficacy of radiofrequency ablation in the treatment of heart failure with different left ventricular ejection fraction(LVEF)combined with persistent atrial fibrillation.Methods:A total of 25 patients with heart failure with mid-range ejection fraction(HFmrEF,LVEF 40%to 49%)and 30 patients with reduced ejection fraction(HFrEF,LVEF<40%)complicated with persistent atrial fibrillation were treated with radiofrequency ablation.All patients underwent atrial fibrillation drug management for 3 months after operation.The related indexes of echocardiography were followed up 6 months after operation.LVEF,left atrium diameter(LAD),left ventricular end-systolic volume(LVESV),left ventricular end-diastolic volume(LVEDV),pulmonary artery pressure,mitral regurgitation(MR),tricuspid regurgitation(TR)of the two groups were recorded before and after operation.Results:After radiofrequency ablation,LVEF in the two groups was higher than that before operation,and LAD,LVESV,LVEDV,and pulmonary artery pressure were lower than those before operation(P<0.05).There was no significant difference in the changes of the above indexes between the two groups(P>0.05).There was no significant difference in the improvement of MR or TR between the two groups(P>0.05).Conclusion:Radiofrequency ablation could improve the clinical indicators of patients with different LVEF heart failure and persistent atrial fibrillation.There is no significant difference in the improvement degree between patients with HFrEF and HFmrEF.
作者
毛冰阳
白雪洋
李凌
MAO Bingyang;BAI Xueyang;LI Ling(Department of Cardiology,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052)
出处
《郑州大学学报（医学版）》
CAS
北大核心
2023年第2期200-204,共5页
Journal of Zhengzhou University(Medical Sciences)
基金
国家自然科学基金项目(81900263,82000262)
河南省医学科技攻关省部共建青年项目(SBGJ202103049)。
关键词
射频消融术
左心室射血分数
心力衰竭
心房颤动
radiofrequency ablation
left ventricular ejection fraction
heart failure
atrial fibrillation
