摘要
目的研制一种新型微型高频超声换能器并检测其对脊柱椎弓根钉道内壁的成像识别能力。方法使用牛髂骨制作4个尺寸为长3 cm、宽1 cm、厚2 mm的皮质骨片,使用电钻在每块骨片的中心钻出直径分别为1、2、3、5 mm的圆孔,模拟椎弓根外层皮质不同大小的穿孔。利用尺寸为3.0 mm×1.0 mm×1.0 mm的30 MHz的微型超声换能器在不同距离对不同大小的皮质骨孔洞进行了成像测量,通过消除传输振铃效应及基于对数函数的灰度映射方法,提高极限近距离分辨能力;通过归一化灰度值曲线精确计算孔径大小,并运用单因素方差分析与实际值进行比较。结果在测量距离≥2 mm时,该高频超声换能器可以检测到直径为5、3、2 mm的孔;在距离为1 mm处,仅5 mm和3 mm的孔可以清晰识别,2 mm的孔存在形变;直径为1 mm的孔在任何距离都无法识别。直径为5 mm、3 mm和2 mm的孔在4 mm、3 mm、2 mm和1 mm 4个不同测试距离下测得的平均校正测量孔径与实际孔径分别比较[(5.07±0.06)、(4.93±0.11)、(4.95±0.07)、(5.01±0.11)mm比5 mm,F=2.166,P>0.05;(3.02±0.06)、(2.96±0.12)、(3.08±0.10)、(2.92±0.08)mm比3 mm,F=2.696,P>0.05]和[(2.01±0.07)、(2.01±0.02)、(2.00±0.10)、(2.05±0.11)mm比2 mm,F=0.403,P>0.05],差异均无统计学意义。结论研制的30 MHz微型超声换能器所能识别的穿孔直径下限为2 mm,近场成像极限距离为1 mm;为进一步研发基于超声的脊柱椎弓根内部成像和导航系统奠定基础。
Objective A new type of miniature high-frequency ultrasonic transducer was developed to test its imaging recognition ability to the inner wall of the pedicle screw canal.Methods The bovine ilium was used to make 4 cortical bone slices with a length of 3 cm,a width of 1 cm and a thickness of 2 mm.The circular holes with diameters of 1,2,3 and 5 mm in the center of each bone slice were drilled by using an electric drill to simulate perforations of different sizes in the outer cortex of the pedicle.The 30 MHz miniature ultrasonic transducer with the size of 3.0 mm×1.0 mm×1.0 mm was used to measure images of cortical bone holes of different sizes at different distances,and the limited short-range resolution was improved after using eliminating transmission ringing effect and logarithmic function-based gray-scale mapping method.The aperture size was calculated accurately by the normalized gray value curve and compared with the actual value by using One-way ANOVA.Results The high-frequency ultrasonic transducer could detect holes with diameters of 5 mm,3 mm and 2 mm when the measurement distance was greater than or equal to 2 mm.At the distance of 1 mm,only 5 mm and 3 mm holes could be clearly identified,and 2 mm holes had deformation.The holes with diameter of 1 mm couldn’t be detected at any distance.The average corrected measuring aperture of holes with diameters of 5 mm,3 mm and 2 mm measured at four different testing distances of 4 mm,3 mm,2 mm and 1 mm was respectively compared with the actual aperture[(5.07±0.06),(4.93±0.11),(4.95±0.07),(5.01±0.11)mm vs.with 5 mm,F=2.166,P>0.05;(3.02±0.06),(2.96±0.12),(3.08±0.10),(2.92±0.08)mm vs.3 mm,F=2.696P>0.05 and(2.01±0.07),(2.01±0.02),(2.00±0.10),(2.05±0.11)mm vs.2 mm,F=0.403P>0.05],and there is no statistically significant differences between the average corrected measuring values and the actual values(P>0.05).Conclusion This study indicats that the minimum diameter of perforation identified by the 30 MHz miniature high-frequency ultrasonic transducer is
作者
李志强
李索远
徐依雯
王强
邵维维
李培洋
焦阳
杨晨
李东泽
崔崤峣
沈军
Li Zhiqiang;Li Suoyuan;Xu Yiwen;Wang Qiang;Shao Weiwei;Li Peiyang;Jiao Yang;Yang Chen;Li Dongze;Cui Yaoyao;Shen Jun(Department of Spine Surgery,the Affiliated Suzhou Hospital of Nanjing Medical University,Suzhou Municipal Hospital,Suzhou 215002,China;Suzhou Institute of Biomedical Engineering and Technology(SIBET),Chinese Academy of Science,Suzhou 215163,China;College of Mechanical and Electrical Engineering,Changchun University of Science and Technology,Changchun 130022,China)
出处
《中华实验外科杂志》
CAS
北大核心
2023年第1期106-110,共5页
Chinese Journal of Experimental Surgery
基金
江苏省社会发展重点项目——临床前沿技术(BE2021659)
苏州市姑苏卫生人才项目(GSWS2020056)。
关键词
脊柱
椎弓根
导航
成像
近距离
超声
Spine
Pedicle
Navigation
Imaging
Close range
Ultrasound
