摘要
目的观察腰痹逐瘀止痛汤联合调脊通督针法治疗气滞血瘀型腰椎间盘突出症(LDH)的疗效及对生活质量的影响。方法将88例气滞血瘀型LDH患者按照随机数字表法分为2组,对照组43例予常规治疗,治疗组45例在对照组治疗基础上加用腰痹逐瘀止痛汤和调脊通督针法治疗,2组均治疗1个月。比较2组治疗前后Oswestry功能障碍指数(ODI)评分、日本骨科协会(JOA)腰椎功能评分变化;比较2组治疗前后中医证候评分变化;比较2组治疗前后生活质量量表(SF-36)评分变化;比较2组治疗前后炎症因子白细胞介素1β(IL-1β)、肿瘤坏死因子α(TNF-α)、IL-6水平变化;比较2组不良反应发生情况。结果2组治疗后ODI评分较本组治疗前降低(P<0.05),JOA腰椎功能评分较本组治疗前升高(P<0.05);治疗后治疗组ODI评分低于对照组(P<0.05),JOA腰椎功能评分高于对照组(P<0.05)。2组治疗后中医证候各项评分均较本组治疗前降低(P<0.05),治疗后治疗组中医证候各项评分均低于对照组(P<0.05)。2组治疗后SF-36各项评分均较本组治疗前升高(P<0.05),治疗后治疗组SF-36各项评分均高于对照组(P<0.05)。2组治疗后IL-1β、TNF-α、IL-6水平均较本组治疗前降低(P<0.05),治疗后治疗组IL-1β、TNF-α、IL-6水平均低于对照组(P<0.05)。治疗组不良反应总发生率13.33%(6/45),对照组不良反应总发生率9.30%(4/43),2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论腰痹逐瘀止痛汤联合调脊通督针法治疗气滞血瘀型LDH,能够抑制炎症,缓解临床症状,改善腰椎功能,提高生活质量,且安全性较高。
Objective To observe the curative effect of Yaobi Zhuyu Zhitong Decoction combined with Tiaojitongdu acupuncture for lumbar disc herniation(LDH)of Qi stagnation and blood stasis and its influence on quality-of-life.Methods Totally 88 LDH patients(Qi stagnation and blood stasis)were randomly assigned into the treatment group(n=45)and the control group(n=43);in addition to the conventional therapy,the treatment group additionally received Yaobi Zhuyu Zhitong Decoction combined with Tiaojitongdu acupuncture.A 1-month treatment was performed to compare Oswestry Disability Index(ODI)scores,Japanese Orthopedic Association(JOA)score,traditional Chinese medicine(TCM)symptom score,Short Form-36 Health Survey(SF-36),inflammatory factors(interleukin-1beta[IL-1β],tumor necrosis factor-α[TNF-α],IL-6);the adverse reactions were assessed.Results After treatment,ODI scores in the both groups were decreased(P<0.05),while JOA scores were increased(P<0.05);reduced ODI scores and elevated JOA scores were found in the treatment group than those of the control group(all P<0.05);TCM symptom scores in the both groups were decreased(P<0.05),which were decreased in the treatment group compared with the control group(P<0.05);SF-36 scores in the both groups were increased(P<0.05),which were increased in the treatment group relative to the control group(P<0.05);IL-1β,TNF-α,IL-6 in the both groups were decreased(P<0.05),the reduction in the treatment group was more prevalent with respect to the control group(P<0.05).The difference was not statistically significant in the total incidence of adverse reactions between the treatment group and the control group(13.33%[6/45]vs 9.30%[4/43],[P>0.05],respectively).Conclusion For LDH patients(Qi stagnation and blood stasis),Yaobi Zhuyu Zhitong Decoction combined with Tiaojitongdu acupuncture can inhibit inflammation,relieve clinical symptoms,improve lumbar function,and improve quality-of-life.
作者
马飞宏
宋志靖
贺智昌
牛爱春
吴建民
李洋
MA Feihong;SONG Zhijing;HE Zhichang;NIU Aichun;WU Jianmin;LI Yang(Gansu University of Chinese Medicine,Lanzhou,Gansu 730030;Department of Rehabilitation Orthopedics,Affiliated Hospital of Gansu University of Chinese Medicine,Lanzhou,Gansu 730030)
出处
《河北中医》
2023年第3期428-432,共5页
Hebei Journal of Traditional Chinese Medicine
关键词
腰椎
椎间盘移位
辨证
中医疗法
针刺疗法
Lumbar vertebrae
Intervertebral disc displacement
Differential diagnosis
Traditional Chinese medicine therapy
Acupuncture therapy
