摘要
目的观察健脾益气生血汤辅助治疗儿童缺铁性贫血脾胃虚弱证的临床疗效。方法选取2020年1—12月丽水市人民医院营养科和儿科门诊收治的缺铁性贫血脾胃虚弱证患儿76例,采用随机数字表法分为对照组和治疗组,各38例。对照组给予蛋白琥珀酸铁口服溶液口服,治疗组在对照组治疗方法的基础上予健脾益气生血汤治疗,2组均连续治疗1个月后统计疗效。结果治疗组总有效率为94.74%(36/38),高于对照组的78.95%(30/38),2组比较,差异有统计学意义(P<0.05)。治疗前2组中医证候积分比较,差异无统计学意义(P>0.05),具有可比性;治疗后2组中医证候积分均明显降低,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组降低更显著(P<0.05)。治疗前2组血清铁蛋白(SF)、铁(SI)、总铁结合力(TIBC)水平比较,差异无统计学意义(P>0.05),具有可比性;治疗后2组SF、SI水平显著升高,TIBC水平显著降低,与同组治疗前比较,差异均有统计学意义(P<0.05),且治疗组升高或降低更显著(P<0.05)。治疗前2组血红蛋白浓度(Hb)、红细胞计数(RBC)、平均红细胞体积(MCV)、平均红细胞血红蛋白浓度(MCHC)水平比较,差异均无统计学意义(P>0.05),具有可比性;治疗后2组上述指标水平均明显升高,与同组治疗前比较,差异均有统计学意义(P<0.05),且治疗组升高更显著(P<0.05)。结论健脾益气生血汤辅助治疗儿童缺铁性贫血脾胃虚弱证,可有效缓解患儿临床症状,改善缺铁情况及红细胞参数,疗效显著,值得临床推广应用。
Objective To observe the clinical efficacy of Jianpi Yiqi Shengxue Tang(健脾益气生血汤)in adjuvant treatment of hypoferric anemia in children with spleen and stomach deficiency syndrome.Methods 76 cases of hypoferric anemia in children with spleen and stomach deficiency syndrome admitted to Nutrition and Pediatric Department of Lishui People’s Hospital between January 2020 and December 2020 were divided into a control group and treatment group (38 cases in each) using a random number table.The control group was given iron proteinsuccinylate oral solution, and the treatment group was treated with Jianpi Yiqi Shengxue Tang on the basis of the control group.We kept statistics about the efficacy after the two groups both received 1 month of consecutive treatment.Results The total effective rate of the treatment group was 94.74%(36/38),which was higher than 78.95%(30/38) of the control group.The difference between the two groups was statistically significant(P<0.05).There was no significant difference in TCM syndrome scores between the two groups before treatment(P>0.05),which was comparable.After treatment,the Chinese medicine syndrome scores in the two groups were decreased significantly when compared with those in the same group before treatment(P<0.05),and the decrease in the treatment group was more significant(P<0.05).There was no significant difference in the levels of serum ferritin(SF),iron(SI) and total iron binding capacity(TIBC) between the two groups before treatment(P>0.05),indicating comparability.After treatment, the levels of SF and SI in the two groups were obviously higher, the levels of TIBC in both groups were obviously lower,the difference was statistically significant in the same group(P<0.05), and the increase or decrease in the treatment group were more significant(P<0.05).Before treatment, there was no significant difference being found in the comparison of the levels of hemoglobin concentration(Hb),red blood cell count(RBC),mean corpuscular volume(MCV) and mean corpuscular hemoglobi
作者
陈阳阳
陈莉
李慧竹
CHEN Yangyang;CHEN Li;LI Huizhu(Department of Nutrition,Lishui People's Hospital,Lishui,Zhejiang,323000,China;Department of Pediatrics,Lishui People's Hospital,Lishui,Zhejiang,323000,China)
出处
《中医儿科杂志》
2023年第1期73-77,共5页
Journal of Pediatrics of Traditional Chinese Medicine
关键词
儿童
缺铁性贫血
脾胃虚弱证
健脾益气生血汤
临床观察
children
hypoferric anemia
spleen and stomach deficiency syndrome
Jianpi Yiqi Shengxue Tang(健脾益气生血汤)
clinical observation
