摘要
目的:探讨非持续性室性心动过速(NSVT)对射血分数保留的心力衰竭(HFpEF)远期预后的影响。方法:以2017年1月至2020年12月期间符合条件的225例HFpEF患者为研究对象,收集一般临床资料。患者于出院前、出院后1周、出院后2周行3次24 h动态心电图监测,记录NSVT发生情况,并据此分为无NSVT组和有NSVT组。所有患者进行前瞻性随访,终点事件为全因死亡。应用寿命表法估算生存率,应用Cox比例风险回归模型分析NSVT和死亡的关系。结果:纳入分析的HFpEF患者215例,共有47例发生NSVT,发生率为21.9%。无NSVT组和有NSVT组之间生存曲线差异有统计学意义(χ^(2)=7.641,P=0.006),无NSVT组生存率高于NSVT组。多因素Cox回归分析表明,NSVT是死亡的危险因素。结论:HFpEF患者有较高的NSVT发生率,并且NSVT影响患者的远期预后,这对于HFpEF患者危险分层、拟定治疗策略具有一定的指导意义。
Objective:To explore the effect of non-sustained ventricular tachycardia(NSVT)on the long-term prognosis of heart failure with preserved ejection fraction(HFpEF).Methods:A total of 225 qualified HFpEF patients from January 2017 to December 2020 were selected as the research objects,and general clinical data were collected.The patients underwent 24 h Holter monitoring three times before discharge,one week after discharge and two weeks after discharge to record the occurrence of NSVT,and were divided into non-NSVT group and NSVT group based on this.Prospective follow-up was performed in all patients.The endpoint event was allcause death.Life table method was used to estimate the survival rate.Multivariate cox proportional hazards regression model was used to analyze the relationship between NSVT and all-cause death.Results:Of 215 HFpEF patients included in the analysis,47 developed NSVT,with an incidence of 21.9%.There was a significant difference in the survival curve between the NSVT-free group and the NSVT group(χ^(2)=7.641,P=0.006).The survival rate of non-NSVT group was higher than that of NSVT group.Multivariate cox proportional hazards regression analysis showed that NSVT was an independent risk factor for death.Conclusion:There is a high incidence of NSVT in patients with HFpEF,and NSVT affects the long-term prognosis of patients,which has certain guiding significance for the risk stratification of HFpEF patients and the formulation of treatment strategies.
作者
许键
贾晓云
杨兴维
Xu Jian;Jia Xiaoyun;Yang Xingwei(Department of Cardiology,The Third People’s Hospital of Nanning,Nanning 530003,China)
出处
《广西医科大学学报》
CAS
2023年第2期310-314,共5页
Journal of Guangxi Medical University
基金
广西壮族自治区卫生健康委员会自筹经费科研课题(No.Z20201309)。
关键词
射血分数保留的心力衰竭
非持续性室性心动过速
预后
heart failure with preserved ejection fraction
non-sustained ventricular tachycardia
prognosis
