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腹腔镜与开腹手术治疗早期胃癌的临床疗效与安全性研究 被引量:1

Study on Clinical Efficacy and Safety of Laparoscopic and Open Surgery for Early Gastric Cancer
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摘要 目的研究腹腔镜手术和开腹手术应用在早期胃癌患者治疗当中的治疗效果和安全性。方法选择2019年1月至2020年5月到我院手术治疗的88例早期胃癌患者按随机方法分为观察组和对照组,每组患者平均为44例。为观察组患者选择腹腔镜手术方案进行治疗,对照组则配合开腹手术治疗,比较两组患者经过不同治疗以后的术中淋巴结清扫总数、手术时间、术中出血量、切口长度、住院时间、并发症发生率、炎性因子水平、生活质量和满意度等。结果①观察组[2例(4.55%)]的并发症发生率明显低于对照组[11例(25.00%)](P<0.05)。②观察组的淋巴结清扫总数明显比对照组更多,手术时间比对照组短,术中出血量比对照组少,切口长度比对照组短,住院时间比对照组短(P<0.05)。③术前,两组患者的IL-6和CRP等指标差异没有显著性(P>0.05),术后24 h和术后72 h,观察组的后IL-6和CRP等指标明显比对照组更低(P<0.05)。④术前,两组患者生活质量评分差异不显著(P>0.05),术后3周,观察组患者的生活质量比对照组更好(P<0.05)。⑤观察组[42例(95.45%)]的满意度比对照组[35例(79.55%)]更高(P<0.05)。结论对早期胃癌患者通过腹腔镜手术方案进行治疗的效果,相比开腹手术而言更好,可以在确保减少并发症的基础上优化术中和术后指标,改善患者的炎性水平,提高患者的生活质量和满意度。 Objective To study the efficacy and safety of laparoscopic surgery and open surgery in the treatment of patients with early gastric cancer.Methods A total of 88 patients with early gastric cancer who underwent surgery in our hospital from January 2019 to May 2020 were selected and randomly divided into an observation group and a control group,with an average of 44 patients in each group.The patients in the observation group were treated with laparoscopic surgery,while the control group was treated with open surgery.The total number of intraoperative lymph node dissection,operation time,intraoperative blood loss,incision length,hospital stay,Complication rate,inflammatory factor levels,quality of life and satisfaction,etc.Results(1)The incidence of complications in the observation group[2 cases(4.55%)]was significantly lower than that in the control group[11 cases(25.00%)](P<0.05).(2)The total number of lymph node dissections in the observation group Significantly more than the control group,shorter operation time,less intraoperative blood loss,shorter incision length,shorter hospital stay than the control group(P<0.05).(3)Before surgery,there was no significant difference in IL-6,CRP and other indicators between the two groups(P>0.05).At 24 h and 72 h after surgery,the postoperative IL-6 and CRP and other indicators in the observation group were significantly lower than those in the control group(P<0.05).(4)Before operation,there was no significant difference in the quality of life scores between the two groups(P>0.05).Three weeks after operation,the quality of life of the observation group was better than that of the control group,and there were some differences between the two groups(P<0.05).(5)The satisfaction of the observation group[42 cases(95.45%)]was higher than that of the control group[35 cases(79.55%)](P<0.05).Conclusion The effect of laparoscopic surgery on patients with early gastric cancer is better than that of laparotomy.It can optimize intraoperative and postoperative indicators on the basis of e
作者 李开明 LI Kaiming(The Second People's Hospital and Gynecology and Obstetrics Hospital of Fuxin City,Fuxin 123000,China)
出处 《中国医药指南》 2023年第9期27-30,共4页 Guide of China Medicine
关键词 腹腔镜 开腹手术 早期胃癌 并发症 炎性因子 生活质量 满意度 Laparoscopy Laparotomy Early gastric cancer Complications Inflammatory factors Quality of life Satisfaction
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