摘要
目的 评价2019年1月-2021年12月温州地区ICU病区耐碳青霉烯类肠杆菌(CRE)的主动筛查方法,并进行CRE定植情况分析、流行病特征汇总分析,为医院感染预防控制提供科学依据。方法 将本院2019年1月-2021年12月ICU病区患者的粪便标本进行麦康凯培养基涂布接种,同时贴10μɡ美罗培南纸片(K-B法)进行筛查试验。用布鲁克全自动快速微生物质谱检测系统鉴定菌种,采用WHONET 5.6软件进行菌种统计分析。结果 入院48 h内主动筛查率为97.48%(464/476),粪便CRE筛查阳性为34株,定植率为7.33%(34/464)。CRE定植分布以肺炎克雷伯为主。侵入性操作是CRE定植或感染的最重要的危险因素。结论 ICU病区CRE定植严重,菌种分布以肺炎克雷伯为主,临床应加强监控。
Objective The active screening method of carbapenem-resistant Enterobacter bacteria(CRE) in the ICU ward in Wenzhou City from January 2019 to December 2021 was evaluated, and the CRE colonization analysis and epidemic characteristics were summarized to provide scientific basis for the prevention and control of nosocomial infection. Methods Fecal samples from patients in the ICU ward from January 2019 to December 2021 were coated with McConkai culture medium, and 10 μɡ meropenem paper sheet(K-B method) was affixed for screening test. Bacterial species were identified using Brooke Automatic Rapid Microbial Mass Spectrometry detection system and statistical analysis was performed using WHONET 5.6 software. Results Within 48 h after admission, the active screening rate was 97.48%(464/476), and fecal CRE screening was positive for 34 strains, and the colonization rate was 7.33%(34/464). The colonization distribution of CRE was mainly Kleber pneumoniae. Invasive procedures are the most important risk factor for CRE colonization or infection. Conclusion CRE colonization in ICU ward is serious, and the strain distribution is mainly Kleber pneumoniae, so clinical monitoring should be strengthened.
作者
陈素菜
陶真
沈丽珍
陈灿
CHEN Su-cai;TAO Zhen;SHEN Li-zhen;CHEN Can(Clinical Laboratory,Wenzhou Hospital of Integrated Chinese and Western Medicine,Zhejiang 325000,China)
出处
《中国卫生检验杂志》
CAS
2023年第4期487-489,共3页
Chinese Journal of Health Laboratory Technology
关键词
耐碳青霉烯类肠杆菌筛查
菌种分布
流行病特征
医院感染
预防控制
CRE screening
Species distribution
Epidemiological characteristics
Nosocomial infection
Prevention and control
