摘要
近年来,富血小板血浆(PRP)在生殖领域的应用取得了突破性进展。研究发现,卵巢内输注自体PRP可有效改善卵巢功能及辅助生殖结局。PRP及其生长因子可刺激卵巢中血管的形成并募集原本不再被激活的原始卵泡,使卵泡数较少或卵泡储备标志物水平较低的卵巢获得新的卵母细胞。本文综述PRP在恢复卵巢卵泡活力以获得卵母细胞及胚胎技术中的应用及相关机制。
In recent years,breakthroughs have been made in the application of platelet-rich plasma(PRP)in the field of reproduction.Studies have found that intraovarian infusion of autologous PRP can effectively improve ovarian function and assisted reproductive outcomes.PRP and its growth factors can stimulate angiogenesis in the ovary and recruit the original follicles that are no longer activated,so as to obtain new oocytes in the ovaries with fewer follicles or low follicular reserve markers.This article reviews the application and mechanism of PRP in restoring the vitality of ovarian follicles to obtain oocytes and embryos.
作者
王蕾童
程东凯
李宝山
李春义
刘双
WANG Leitong;CHENG Dongkai;LI Baoshan;LI Chunyi;LIU Shuang(Assisted Reproduction Laboratory,Shenyang Jinghua Hospital,Liaoning Province,Shenyang 110000,China)
出处
《妇儿健康导刊》
2023年第5期23-25,34,共4页
JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
关键词
富血小板血浆
卵巢早衰
卵母细胞
辅助生殖技术
Platelet-rich plasma
Premature ovarian failure
Oocyte
Assist ed reproductive technology
