摘要
目的 探讨扎赉特旗布鲁氏菌病的变化趋势、主要传播途径及其影响因素,从而有效防控布鲁氏菌病的发生。方法 2021年10月至2022年8月利用流行病学、虎红平板凝集试验、布鲁菌试管抗体凝集和血培养等方法对扎赉特旗997例居民患布鲁氏菌病情况进行监测和分析。结果 扎赉特旗A区居民布鲁氏菌病患病率为4.0%(19/476),B区居民患病率为4.4%(23/521),总患病率为4.2%(42/997)。该地区春秋两季为布鲁氏菌病的高发季节。患布鲁氏菌病者与未患布鲁氏菌病者在外来牲畜检疫检测情况方面的差异无统计学意义(P>0.05),在性别、牲畜接触史、接羔/犊时是否戴手套和口罩、接触牲畜后手卫生次数、自家死畜是否进行深度填埋方面均存在明显差异(P<0.05)。多因素Logistic回归分析显示有牛羊接触史、接羔/犊时未戴手套和口罩、接触牲畜后手卫生次数≤1次、自家死畜未进行深度填埋是患布鲁氏菌病的危险因素(P<0.05)。与未患布鲁氏菌病者相比,多数布鲁氏菌病患者具有发热、关节酸痛、乏力、多汗等临床症状(P<0.05)。结论 扎赉特旗患布鲁氏菌病的人群多出现发热、关节疼痛、乏力以及多汗等症状;男性较女性更容易患病;该地区布鲁氏菌病患病率略高的原因可能是生产过程中防护措施不当等;春秋两季为当地畜牧生产旺季,同时也是布鲁氏菌病高发的季节。
Objective To explore the change trend,main transmission routes and influencing factors of brucellosis in Zhalaite Banner so as to effectively prevent and control the occurrence of brucellosis.Methods A total of 997 residents in Zalait Banner from October 2021 to August 2022 were monitored and analyzed for brucellosis by means of epidemiology,tiger red plate agglutination test,Brucella test tube antibody agglutination and blood culture.Results The prevalence rate of brucellosis among the residents in Zhalaite Banner District A was 4.0%(19/476),and that of the residents in the District B was 4.4%(23/521),with a total prevalence rate of 4.2%(42/997).Spring and autumn were the high incidence seasons of brucellosis in this area.There was no statistically significant difference in the quarantine and detection of foreign livestock between brucellosis patients and non-brucellosis patients(P>0.05),but there were significant differences in the gender,livestock contact history,whether wearing gloves and masks when lambing/calving,number of hand hygiene after contacting with livestock,and whether the dead animals were buried in depth(P<0.05).The multivariate Logistic regression analysis showed that the risk factors of brucellosis were the history of contacting with cattle and sheep,without wearing the gloves and masks during lambing/calving,hand hygiene frequency after contacting with livestock ≤ once and the absence of deep landfill of dead livestock(P<0.05).Compared with non-brucellosis patients,most patients with brucellosis had clinical signs such as fever,arthralgia,fatigue and hyperhidrosis(P<0.05).Conclusion The people suffering from brucellosis in Zhalaite Banner all appeared the signs such as fever,joint pain,fatigue and hyperhidrosis;men are more likely to get sick than women;the reason for the slightly higher prevalence rate of brucellosis in this area may be closely related to factors such as the improper protective measures during the production process;spring and autumn are the peak periods for local livestoc
作者
吴晓东
张少林
达尔罕
张芳芳
柏东
王丹
袁海涛
那钦
邵红星
WU Xiaodong;ZHANG Shaolin;Darhan;ZHANG Fangfang;BAI Dong;WANG Dan;YUAN Haitao;Naqin;SHAO Hongxing(Department of Clinical Laboratory,Xing′an League Center for Disease Control and Prevention of Inner Mongolia Autonomous Region,Xing′an,Inner Mongolia137400,China;Institute of Pharmacology,Shandong First Medical University,Tai′an,Shandong 271016,China;Department of Local Diseases,Xing′an League Center for Disease Control and Prevention,Xing′an,Inner Mongolia 137400,China;Rural Revitalization Office of Party Committee of Huasumu People′s Government of Baoligen,Zhalaite Banner,Inner Mongolia Autonomous Region,Xing′an,Inner Mongolia 137617,China)
出处
《检验医学与临床》
CAS
2023年第6期732-735,共4页
Laboratory Medicine and Clinic
基金
国家自然科学基金青年科学基金项目(81803510)。
