摘要
目的观察吴茱萸热奄包对重症缺血性脑卒中伴有肠功能障碍患者的临床疗效。方法选取2019年6月至2021年6月在我院诊治的重症缺血性脑卒中伴有肠功能障碍患者96例纳入研究,按照数字表法随机分为两组,每组各有48例,所有入选者均给予控制颅内压、改善微循环、保护胃黏膜等对症支持治疗,在常规治疗基础上对照组行肠内营养支持,并给予双歧杆菌活菌1粒/次,2次/日,鼻饲注入。在对照组基础上观察组给予吴茱萸热奄包治疗,2次/日。治疗7天时对比两组患者营养指标及肠黏膜屏障指标。结果治疗7天时观察组患者营养指标及肠黏膜屏障指标均高于对照组(P<0.05);对照组患者营养指标:血清TP、ALB及Hb水平与治疗前相当(P>0.05),观察组患者血清TP、ALB及Hb水平优于治疗前(P<0.05)。两组患者肠黏膜屏障指标:血清DAO及ETX水平分别与治疗前比较差异均有统计学意义(P<0.05)。结论吴茱萸热奄包使用方便,且效果满意,可有效改善重症缺血性脑卒中伴有肠功能障碍患者营养状况及肠黏膜屏障功能,值得推广。
Objective To observe the clinical effect of Evodia rutaecarpa Rehai Bao on severe ischemic stroke patients with intestinal dysfunction.Methods 96 patients with severe ischemic stroke and intestinal dysfunction who were diagnosed and treated in our hospital from June 2019 to June 2021 were included in the study.They were randomly divided into two groups according to the digital table method,with 48 patients in each group.All the selected patients were given symptomatic support treatment such as controlling intracranial pressure,improving microcirculation,protecting gastric mucosa,etc.On the basis of conventional treatment,the control group was given enteral nutrition support,and given live bifidobacterium 1 capsule/time,2 times/day,nasal feeding injection.On the basis of the control group,the observation group was given the treatment of Evodia rutaecarpa heat package,twice a day.After 7 days of treatment,the nutritional index and intestinal mucosal barrier index of the two groups were compared.Results On the 7th day of treatment,the nutritional index and intestinal mucosal barrier index of patients in the observation group were higher than those in the control group(P<0.05);The nutritional indexes of patients in the control group:the serum levels of TP,ALB and Hb were similar to those before treatment(P>0.05),while the serum levels of TP,ALB and Hb in the observation group were better than those before treatment(P<0.05).There were statistically significant differences between the two groups in intestinal mucosal barrier indicators:serum DAO and ETX levels before and after treatment(P<0.05).Conclusion Evodia rutaecarpa hot bag is convenient to use,and the effect is satisfactory.It can effectively improve the nutritional status and intestinal mucosal barrier function of patients with severe ischemic stroke accompanied by intestinal dysfunction,and is worthy of promotion.
作者
谢晓华
Xie Xiao-hua(People's Hospital affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou 350004,Fujian Province,China)
出处
《罕少疾病杂志》
2023年第3期10-12,共3页
Journal of Rare and Uncommon Diseases
关键词
吴茱萸热奄包
缺血性脑卒中
肠功能障碍
营养状况
肠黏膜屏障
Evodia Rutaecarpa
Ischemic Stroke
Intestinal Dysfunction
Nutritional Status
Intestinal Mucosal Barrier
