摘要
目的探讨老年慢性阻塞性肺疾病(COPD)患者衰弱期及衰弱前期的影响因素。方法采用便利抽样法,选取2021年11月至2022年5月于新疆维吾尔自治区人民医院呼吸内科住院的326例老年COPD患者作为研究对象,采用一般资料调查表、Morse跌倒风险评估量表、COPD评估测试量表、匹兹堡睡眠质量指数量表、微型营养评定量表、简版老年抑郁量表、社会支持评定量表进行问卷调查,同时收集患者实验室相关指标,采用无序多分类logistic回归分析影响老年COPD患者衰弱的因素。采用SPSS 26.0软件进行统计分析。根据数据类型,组间比较分别采用方差分析、秩和检验及χ^(2)检验。结果老年COPD患者衰弱患病率为39.57%(129/326),衰弱前期患病率为34.05%(111/326)。无序多分类logistic回归分析结果显示,女性、多重用药、存在睡眠问题、营养不良以及高B型利钠肽是其共同的影响因素。而高龄(OR=1.090,95%CI 1.027~1.157;P=0.004)、体质量指数<23.9 kg/m^(2)(OR=0.109,95%CI 0.042~0.283;P<0.001)、社会支持(OR=4.621,95%CI 1.222~17.470;P=0.024)和高血红蛋白(OR=1.042,95%CI 1.007~1.078;P=0.018)只对老年COPD患者衰弱前期有影响;COPD评估测试量表评分(OR=11.962,95%CI 3.056~46.831;P<0.001)、肺功能分级在重度及以上水平(OR=8.094,95%CI 1.862~35.188;P=0.005)和抑郁(OR=27.177,95%CI 2.811~262.705;P=0.004)只对老年COPD患者衰弱期有影响。结论老年COPD患者衰弱及衰弱前期的发生率相对较高,不同程度的衰弱影响因素存在差异,应采取不同的个性化干预措施,预防衰弱前期的发生,同时控制并逆转衰弱。
Objective To explore the influencing factors of frailty and pre-frailty in the elderly patients with chronic obstructive pulmonary disease(COPD).Methods Using the convenient sampling method,a total of 326 elderly COPD patients hospitalized in the Department of Respiratory Diseases of the People's Hospital of Xinjiang Uygur Autonomous Region from November 2021 to May 2022 were selected as the research subjects.A questionnaire survey was conducted,and the patients′related laboratory indicators were collected using the general information questionnaire,Morse fall scale,COPD assessment test,Pittsburgh sleep quality index,short-form mini-nutritional assessment,15-item geriatric depression scale,and social support rating scale.Unordered multinomial logistic regression analysis was performed to explore the influencing factors of frailty in the elderly COPD patients.SPSS 26.0 was used for statistical analysis.Depending on data type,variance analysis,rank sum test orχ^(2)test were used for data comparison between two groups.Results The prevalence of frailty and pre-frailty was 39.57%(129/326)and 34.05%(111/326)in the elderly COPD patients.The unordered multiple logistic regression analysis showed that being female,multiple medications,sleep problems,malnutrition and high B-type natriuretic peptide were the common influencing factors.However,age(OR=1.090,95%CI 1.027-1.157;P=0.004),body mass index<23.9 kg/m 2(OR=0.109,95%CI 0.042-0.283;P<0.001),social support(OR=4.621,95%CI 1.222-17.470;P=0.024)and high hemoglobin(OR=1.042,95%CI 1.007-1.078;P=0.018)only affected pre-frailty.COPD assessment test score(OR=11.962,95%CI 3.056-46.831;P<0.001),pulmonary function GOLD grade(OR=8.094,95%CI 1.862-35.188;P=0.005)and depression(OR=27.177,95%CI 2.811-262.705;P=0.004)only affected the frailty.Conclusion The incidence of frailty and pre-frailty in the elderly COPD patients is relatively high,and different influencing factors affect frailty in different degrees.Different personalized intervention measures should be taken to prevent the
作者
段菲
赵士红
孙小卫
肖江琴
Duan Fei;Zhao Shihong;Sun Xiaowei;Xiao Jiangqin(Department of Nursing Administration,People′s Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830000,China)
出处
《中华老年多器官疾病杂志》
2023年第2期91-96,共6页
Chinese Journal of Multiple Organ Diseases in the Elderly
基金
新疆维吾尔自治区自然科学基金(2022D01C111)。
关键词
慢性阻塞性肺疾病
衰弱
衰弱前期
影响因素
chronic obstructive pulmonary disease
frailty
pre-frailty
influencing factors
