摘要
目的探讨退黄外洗方药浴联合穴位贴敷治疗新生儿黄疸的效果与安全性。方法采用前瞻性随机对照研究方法,纳入焦作市妇幼保健院2019年6月至2021年6月收治的110例新生儿黄疸患儿,按随机数字表法分为观察组和对照组,每组55例。对照组采用茵栀黄颗粒、酪酸杆菌治疗,观察组在对照组基础上采用退黄外洗方药浴联合穴位贴敷治疗,均治疗7 d。观察两组治疗7 d时的效果;记录并分析两组胎便排空时间、大便次数、黄疸消退时间与日均胆红素下降值;比较两组治疗前后血清胆红素、直接胆红素、白蛋白水平;统计两组不良反应发生率。结果观察组治疗7 d时总有效率(94.55%,52/55)高于对照组(81.82%,45/55),P<0.05;观察组胎便排空时间、黄疸消退时间短于对照组,大便次数多于对照组,日均胆红素下降值高于对照组(P<0.05);治疗7 d时,观察组血清总胆红素、直接胆红素、白蛋白水平低于对照组(P<0.05);两组不良反应发生率比较差异未见统计学意义(P>0.05)。结论退黄外洗方药浴联合穴位贴敷治疗新生儿黄疸,能有效降低血清总胆红素、间接胆红素、白蛋白水平,促进黄疸消退,提高疗效。
Objective To investigate the efficacy and safety of Tuihuang external washing prescription combined with acupoint compress in the treatment of neonatal jaundice.Methods This study was a prospective randomized controlled study.A total of 110 infants with neonatal jaundice treated in Maternal and Child Health Care Hospital of Jiaozuo from June 2019 to June 2021 were enrolled in the study.And selected infants were divided into observation group and control group according to the random number table method,with 55 cases in each group.The control group was treated with Yinzhihuang granule and butyrobacter,and the observation group was treated with Tuihuang external washing prescription combined with acupoint compress based on the treatment of the control group,both groups were treated for 7 days.The curative effect of the two groups after 7 days of treatment were observed.The fetal stool emptying time,stool frequency,jaundice regression time and daily average bilirubin decline in the two groups were recorded and analyzed.The levels of serum bilirubin,direct bilirubin and albumin were compared between the two groups before and after treatment.The incidence of adverse reactions of the two groups were counted.Results The total effective rate of the observation group(94.55%,52/55)was higher than that of the control group(81.82%,45/55)after 7 days of treatment(P<0.05).The fetal stool emptying time and jaundice regression time of the observation group were shorter than those of the control group,the stool frequency was more than that of the control group,and the daily average bilirubin decline value was higher than that of the control group(P<0.05).Compared with the control group,the levels of serum total bilirubin,direct bilirubin and albumin in the observation group were lower after 7 days of treatment(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions The treatment of neonatal jaundice with Tuihuang external washing prescription combined with acupo
作者
何燕娜
段洁
沈瑞翔
张静
He Yanna;Duan Jie;Shen Ruixiang;Zhang Jing(Department of Traditional Chinese Medicine,Maternal and Child Health Care Hospital of Jiaozuo,Jiaozuo 454001,China)
出处
《中国实用医刊》
2022年第23期120-122,F0003,共4页
Chinese Journal of Practical Medicine
基金
焦作市科技计划项目(2020-40-193)。
关键词
新生儿黄疸
退黄外洗方药浴
穴位贴敷
胆红素
Neonatal jaundice
Tuihuang external washing prescription
Acupoint application
Bilirubin
