摘要
目的探讨内镜黏膜下剥离术治疗的临床效果,归纳分析引起术后出血的相关危险因素.方法选择2017年3月-2022年3月在泰州市第二人民医院接受内镜黏膜下剥离术治疗的患者100例作为研究对象,观察治疗效果,统计患者发生术后出血并发症的总概率,结合患者一般资料、疾病信息等归纳总结引起出血的相关危险因素.结果100例患者接受内镜黏膜下剥离术治疗后,均成功切除病灶,手术成功率为100.00%,15例患者出现不同程度出血情况,占比15.00%.单因素分析出血因素结果显示,出血与未出血患者性别、年龄因素比较,无统计学差异(P>0.05),出血患者病灶位于贲门-胃底部、病灶直径超过15mm、早癌及术前长时间服用抗凝药物占比率高于未出血患者(P<0.05);多因素分析结果显示,病灶位置、病灶直径、早癌、术前抗凝药物均为引起术后出血的独立危险因素.结论内镜黏膜下剥离术治疗消化道疾病具有显著效果,应结合患者一般资料、疾病信息等分析出血危险因素,做好针对性预防,保障患者治疗安全.
Objective To explore the clinical effect of endoscopic submucosal dissection,and summarize and analyze the related risk factors for postoperative bleeding.Methods 100 patients who underwent endoscopic submucosal dissection in our hospital from March 2017 to March 2022 were selected as the study objects to observe the treatment effect,count the total probability of postoperative bleeding complications,and summarize the relevant risk factors of bleeding in combination with the general information and disease information of patients.Results After receiving endoscopic submucosal dissection,all 100 patients successfully resected the lesions,with a success rate of 100.00%.15 patients had bleeding to varying degrees after operation,accounting for 15.00%.The results of univariate analysis of bleeding factors showed that there was no statistical difference between the patients with bleeding and those without bleeding in terms of gender and age(P>0.05).The proportion of patients with bleeding whose focus was located at the bottom of cardia stomach,whose diameter was more than 15mm,early cancer and taking anticoagulants for a long time before operation was higher than that of patients without bleeding(P<0.05).The results of multivariate analysis showed that the location of focus,diameter of focus,early preoperative anticoagulants were independent risk factors for postoperative bleeding.Conclusion Endoscopic submucosal dissection has a significant effect on the treatment of digestive tract diseases.We should analyze the risk factors of bleeding in combination with the general information and disease information of patients,and do a targeted prevention to ensure the safety of patients'treatment.
作者
赵福军
Zhao Fujun(Department of Gastroenterology of Taizhou Second People's Hospital,Taizhou,Jiangsu 225300,China)
出处
《首都食品与医药》
2023年第3期41-43,共3页
Capital Food Medicine
关键词
内镜黏膜下剥离术
疗效
出血
危险因素
Endoscopic submucosal dissection
Curative effect
Bleeding
Risk factors
