摘要
目的:观察门冬氨酸钾镁联合胺碘酮治疗急性心肌梗死患者的效果。方法:选取2018年1月至2020年4月该院收治的108例急性心肌梗死患者进行前瞻性研究,按照随机数字表法分为对照组和观察组各54例。对照组采用盐酸胺碘酮注射液治疗,观察组在对照组基础上联合门冬氨酸钾镁注射液治疗。比较两组临床疗效,治疗前后心功能指标[左心室射血分数(LVEF)、左心室舒张末期内径(LVEDD)、左室后壁厚度(LVPWD)]水平,以及不良反应发生率。结果:观察组治疗总有效率为94.44%(51/54),高于对照组的81.48%(44/54),差异有统计学意义(P<0.05);治疗后,两组LVEF水平均高于治疗前,且观察组高于对照组,两组LVEDD、LVPWD水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:门冬氨酸钾镁联合胺碘酮治疗急性心肌梗死患者可提高治疗总有效率,改善心功能指标水平,效果优于单纯胺碘酮治疗。
Objective:To observe effects of Potassium aspartate and magnesium aspartate injection combined with Amiodarone in treatment of patients with acute myocardial infarction.Methods:A prospective study was conducted on 108 patients with acute myocardial infarction admitted to the hospital from January 2018 to April 2020.They were divided into control group and observation group according to the random number table method,54 cases in each.The control group was treated with Amiodarone hydrochloride injection,while the observation group was treated with Potassium magnesium aspartate injection on the basis of that of the control group.The clinical efficacy,the cardiac function index levels[left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD),left ventricular posterior wall thickness(LVPWD)],and incidence of adverse reactions were compared between the two groups before and after the treatment.Results:The total effective rate of treatment in the observation group was 94.44%(51/54),which was higher than 81.48%(44/54)in the control group,and the difference was statistically significant(P<0.05).After the treatment,the LVEF levels of the two groups were higher than those before the treatment,and that of the observation group was higher than that of the control group;the levels of LVEDD and LVPWD in the two groups were lower than those before the treatment,and those in the observation group were lower than those in the control group;and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Potassium aspartate and magnesium aspartate combined with Amiodarone in the treatment of the patients with acute myocardial infarction can improve the total effective rate of treatment and improve the levels of cardiac function indexes.Moreover,it is superior to single Amiodarone treatment.
作者
苏文刚
SU Wen'gang(Department of Cardiology of Nanyang First People’s Hospital,Nanyang 473000 Henan,China)
出处
《中国民康医学》
2023年第3期21-23,共3页
Medical Journal of Chinese People’s Health
关键词
急性心肌梗死
门冬氨酸钾镁
胺碘酮
心功能
不良反应
Acute myocardial infarction
Potassium aspartate and magnesium aspartate
Amiodarone
Cardiac function
Adverse reaction
