摘要
前庭性偏头痛(VM)是临床常见的具有遗传倾向、以反复发作性眩晕或头晕、可伴恶心呕吐、伴或不伴头痛的一种疾病。目前关于VM的诊断主要依据临床表现,但其临床表现差异大且易与其他前庭疾病混淆,听前庭功能检查常提示轻度受损或正常,尚未发现对VM诊断有特异性价值的临床体征或实验室检查。多项磁共振成像研究表明偏头痛患者多处脑区存在结构和功能改变,但目前关于VM涉及的脑区及病理生理机制研究有限。基于此本文对VM的临床特点、听力和前庭功能检查、磁共振成像研究现况及其可能的发病机制进行综述,并探讨进一步的研究趋势。
Vestibular migraine is a common clinical disease,with genetic predisposition,characterized by recurrent paroxysmal vertigo or dizziness,which can be accompanied by nausea,vomiting or headache.At present,the diagnosis of vestibular migraine is mainly based on clinical manifestations,but a variety of clinical manifestations are easy to be confused with other vestibular diseases,hearing and vestibular function tests often indicate mildly impaired or normal.No specific clinical signs or laboratory examinations have been found to help diagnose vestibular migraine.A number of magnetic resonance imaging studies have shown that there are structural and functional changes in many brain regions of migraine patients,but the current research on brain regions and pathophysiological mechanisms involved in vestibular migraine is limited.Based on this,this article reviews the current research status and possible pathogenesis of vestibular migraine,including clinical manifestations,hearing and vestibular function tests,magnetic resonance imaging,and discusses further research trends.
作者
韩淋
张凯
方琪
HAN Lin;ZHANG Kai;FANG Qi(The First Affiliated Hospital of Soochow University,Suzhou 215006,China)
出处
《中国实用神经疾病杂志》
2022年第11期1447-1452,共6页
Chinese Journal of Practical Nervous Diseases
基金
国家自然科学基金面上项目(编号:82071300)。
关键词
前庭性偏头痛
临床特点
听力和前庭功能检查
磁共振成像
发病机制
Vestibular migraine
Clinical manifestations
Hearing and vestibular function tests
Magnetic resonance imaging
Pathogenesis
