摘要
目的探究成年人视网膜动脉硬化与全身因素的相关性。方法回顾性临床研究,收集2020年1月至12月在广州市第十一人民医院健康体检时自愿接受眼科检查的广州市公职人员9361例,所有受检者均询问既往眼科和内科病史并记录、测量身高、体质量、血压,血液检查包括血常规、空腹血糖、血脂六项、血尿酸等。所有受检者均在暗室环境下采用免散瞳眼底照相机对其进行双眼眼底彩照拍摄。由具有丰富临床经验的4名眼科医师对眼底照相结果进行诊断。采用SPSS 26.0对视网膜动脉硬化与全身因素进行单因素及多因素Logistic回归分析。结果单因素Logistic回归分析显示女性、年龄增长、超重、肥胖、高血压、糖尿病的人群患病风险增加(P<0.05)。多因素Logistic回归模型提示,50岁以上年龄[50~59岁(OR:4.63,OR的95%CI:3.35,6.40);60~69岁(OR:39.32,OR的95%CI:28.51,54.23);≥70岁(OR:77.87,OR的95%CI:56.12,108.06)]、高血压(OR:3.35,OR的95%CI:2.93,3.81)、肥胖(OR:1.70,OR的95%CI:1.40,2.08)为视网膜动脉硬化的独立危险因素(P<0.001)。结论50岁以上年龄、高血压、肥胖为视网膜动脉硬化的主要危险因素,临床工作中应对风险人群早期识别,早期诊断和早期治疗,以降低心血管事件的发生。
Objective To explore the correlation between adult retinal arteriosclerosis and systemic factors.Methods A retrospective clinical study was performed on 9361 civil servants who voluntarily underwent eye examination during physical examination in the 11th People's Hospital of Guangzhou from January to December 2020.All the subjects were asked about previous ophthalmic and internal medical history,and their height,body weight and blood pressure were recorded and measured.Blood test included routine blood test,fasting blood glucose,blood lipid six items,blood uric acid,etc.Binocular fundus color photographs were taken by a non-dilatatory fundus camera in a dark room.The diagnosis was made by 4 ophthalmologists with rich clinical experience.Univariate and multivariate Logistic regression analysis of retinal arteriosclerosis and systemic factors was performed by SPSS 26.0.Results Univariate Logistic regression analysis showed that the risk of female patients with aging,overweight,obesity,hypertension and diabetes increased(P<0.05).Multivariate Logistic regression model suggested that age above 50 years old[50~59 years old(OR:4.63,OR 95%CI:3.35,6.40);60~69 years old(OR:39.32,OR 95%CI:28.51,54.23);≥70 years old(OR:77.87,OR 95%CI:56.12,108.06)],hypertension(OR:3.35,OR 95%CI:2.93,3.81),obesity(OR:1.70,OR 95%CI:1.40,2.08)were independent risk factors for retinal arteriosclerosis(P<0.001).Conclusion Age over 50 years old,hypertension and obesity are the main risk factors for retinal arteriosclerosis.In clinical work,early identification,early diagnosis and early treatment should be carried out to reduce the occurrence of cardiovascular events.
作者
杨唐健
江瑜
周勇
余莎
陈彩环
YANG Tang-Jian;JIANG Yu;ZHOU Yong;YU Sha;CHEN Cai-huan
出处
《中国疗养医学》
2023年第4期441-444,共4页
Chinese Journal of Convalescent Medicine
关键词
视网膜动脉硬化
全身因素
相关性
Retinal arteriosclerosis
Systemic factors
Correlation
