摘要
目的 观察颅内血肿微创手术及手术后与尿激酶联合应用的临床治疗效果。方法 选取2020年6月~2022年6月我院因高血压基底节脑出血患者75例,分为常规组与观察组,常规组微创行颅内血肿清除术,观察组在颅内血肿清除基础上,应用尿激酶冲洗血肿腔。比较两组患者手术后神经功能恢复状况、昏迷程度评分情况、日常生活能力评分、运动评分、术后生活质量评分、术后并发症发生率情况。结果 观察组患者脑内血肿清除手术后神经功能缺损的程度较常规组患者低,P<0.05;观察组患者手术后昏迷程度评分高于常规未应用尿激酶组患者,P<0.05;与常规未应用尿激酶组相比,观察组患者日常生活能力评分更高,P<0.05;观察组患者术后运动能力评分好于常规组患者,P<0.05;观察组的生活质量较常规组存在较大的差异,常规组患者生活质量更低,P<0.05;观察组患者微创手术后并发症的发生率低于常规组患者,P<0.05。结论 颅内血肿微创手术及手术后与尿激酶的联合应用促进血肿排出,能够有效改善患者神经功能,促进神经康复,手术后并发症发生率较低,值得临床推广。
Objective To investigate the clinical therapeutic effect of urokinase flushing hematoma cavity and minimally invasive surgical puncture for intracranial hematoma removal after operation.Methods From June 2020 to June 2022,a total of 75 patients with hypertensive basal ganglia intracerebral hemorrhage treated in our hospital were divided into routine group and observation group.The routine group underwent minimally invasive removal of intracranial hematoma, and the observation group rinsed the hematoma cavity with urokinase on the basis of removal of intracranial hematoma.The neurological recovery, coma degree score, ability of daily living score, exercise score, postoperative quality of life score and the incidence of postoperative complications were compared between the two groups.Results The degree of neurological deficit in the observation group was lower than that in the routine group(P<0.05);The coma degree score in the observation group was higher than that in the routine non-urokinase group(P<0.05);Compared with the routine group, the scores of ADL in the observation group were higher(P<0.05);The postoperative motor ability score of the observation group was better than that of the routine group(P<0.05);The quality of life was lower in the routine group than that in the observation group, which was significantly different(P<0.05);The incidence of complications after minimally invasive surgery in the observation group was lower than that in the routine group(P<0.05).Conclusion Minimally invasive surgery for intracranial hematoma removal and the combined application of urokinase after operation to promote hematoma excretion can effectively improve patients’ neurological function and promote neurological rehabilitation.The incidence of postoperative complications is low, which can be actively promoted.
作者
张凯
林超
郑洪彩
ZHANG Kai;LIN Chao;ZHENG Hongcai(Department of Surgery,Weifang Medical University,Weifang 261053,China;Department of Science and Education,Zhucheng People's Hospital;Department of Neurosurgery,Zhucheng People's Hospital)
出处
《潍坊医学院学报》
2022年第6期408-411,共4页
Acta Academiae Medicinae Weifang
关键词
微创
血肿清除手术
尿激酶
基底节脑出血
神经康复
并发症
Minimally invasive
Removal of intracranial hematoma
Urokinase
Basal ganglia hemorrhage
Neurological rehabilitation
Complications
