摘要
甜菊糖苷是一种从甜叶菊叶片中提取的高甜度、零热量甜味剂,可用作食品添加剂。近年来,甜菊糖苷在国内外市场需求量剧增,引起了广泛关注。概述国际上对甜菊糖苷的安全性研究及评价,从经济价值角度分析甜菊糖苷的市场需求及应用前景,总结甜菊糖苷作为食品甜味添加剂的应用以及其在抗糖尿病、抗心脏纤维化、抗菌等保健功能方面的最新研究成果。综述甜菊糖苷的生物合成研究进展,重点介绍甜菊糖苷的微生物体从头合成以及生物催化低甜度糖苷生成高甜度、口感更优的甜菊糖苷,探讨提高甜菊糖苷产量的关键因素,为高端甜味剂绿色合成工艺的研究与开发提供理论依据。
Steviol glycosides are high-sweetness and zero-calorie sweeteners extracted from Stevia leaves. They can be used as food additives, and their demand in domestic and foreign markets has increased sharply, drawing widespread attention. The review discusses the safety research and evaluation of steviol glycosides in the world and analyzes the market demand and prospects of steviol glycosides from the perspective of economic value. Then, it summarizes the application of steviol glycosides as a sweetener in food and the latest research results in their anti-diabetic, anti-cardiac fibrosis, anti-bacterial and other health-care functions. The research progress in the production, preparation and biosynthesis of steviol glycosides is reviewed, with an emphasis on their de novo synthesis in microorganisms, and the latest progress in the biocatalytic conversion of low-sweet glycosides to produce steviol glycosides with higher sweetness and better taste. Finally, several key strategies for improving production of steviol glycosides are mentioned, and their future development prospects are discussed, providing a theoretical basis for the research and development of green synthesis process of high-end sweeteners.
作者
李亚桐
马媛媛
汪振洋
宋浩
LI Ya-tong;MA Yuan-yuan;WANG Zhen-yang;SONG Hao(School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China;School of Marine Science and Technology,Tianjin University,Tianjin 300072,China;Tianjin R&D Center for Petrochemical Technology,Tianjin University,Tianjin 300072,China;R&D Division,Sinochem Health Company Ltd.,Qingdao 266071,China;Qingdao Institute of Ocean Engineering of Tianjin University Ltd.,Qingdao 266237,China)
出处
《中国生物工程杂志》
CAS
CSCD
北大核心
2023年第1期104-114,共11页
China Biotechnology
基金
天津市自然科学基金(18JCYBIC24200)资助项目。
