麝香保心丸、复方丹参滴丸与脑心通胶囊治疗冠心病稳定型心绞痛的药物经济学评价被引量：9

Pharmacoecomic Evaluation on Shexiang Baoxin Pills,Compound Danshen Dropping Pills and Naoxintong Capsules in the Treatment of Stable Angina Pectoris of Coronary Heart Disease

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摘要目的:评价麝香保心丸、复方丹参滴丸与脑心通胶囊治疗冠心病稳定型心绞痛的经济性。方法:从卫生体系角度出发,构建决策树模型,采用成本-效用分析,对麝香保心丸、复方丹参滴丸与脑心通胶囊治疗冠心病稳定型心绞痛进行药物经济学评价。结果:与麝香保心丸组比较,脑心通胶囊组方案的增量成本-效用比为3501593.41,>3倍人均GDP,麝香保心丸组方案更具有经济性;与复方丹参滴丸组比较,麝香保心丸组方案的成本更低,效果更好;因此,麝香保心丸组方案最具有经济性。敏感性分析显示结果具有稳健性。结论:与复方丹参滴丸、脑心通胶囊比较,麝香保心丸治疗冠心病稳定型心绞痛更具有药物经济学优势。 OBJECTIVE:To evaluate the economical efficiency of Shexiang Baoxin pills,compound Danshen dropping pills and Naoxintong capsules in the treatment of stable angina pectoris of coronary heart disease.METHODS:Based on the perspective of health system,a decision tree model was constructed,and cost-utility analysis was used to conduct pharmacoeconomic evaluation on Shexiang Baoxin pills,compound Danshen dripping pills and Naoxintong capsules in the treatment of stable angina pectoris of coronary heart disease.RESULTS:Compared with the Shexiang Baoxin pills group,the incremental cost-utility ratio of the Naoxintong capsules group regimen was 3501593.41,which was greater than 3 times the GDP per capita,so that the Shexiang Baoxin pills group regimen was more economical;compared with the compound Danshin dropping pills group,the Shexiang Baoxin pills group regimen was less costly and more effective;therefore,the Shexiang Baoxin pills group regimen was the most economical.Sensitivity analysis showed that the results were robust.CONCLUSIONS:Compared with compound Danshin dropping pills and Naoxintong capsules,the Shexiang Baoxin pills has more pharmacoeconomic advantages in the treatment of stable angina pectoris in coronary heart disease.

作者王晓丽董占军张慧玲袁耀辉种宝贵刘国强 WANG Xiaoli;DONG Zhanjun;ZHANG Huiling;YUAN Yaohui;CHONG Baogui;LIU Guoqiang(Dept.of Pharmacy,the Third Hospital of Hebei Medical University,Shijiazhuang 050000,China;Dept.of Pharmacy,Hebei General Hospital,Shijiazhuang 050000,China;Dept.of Traditional Chinese Medicine,the Third Hospital of Hebei Medical University,Shijiazhuang 050000,China;Dept.of Pharmacy,the Third Hospital of Xingtai,Hebei Xingtai 054000,China;Dept.of Pharmacy,Harrison International Peace Hospital,Hebei Hengshui 053000,China)

机构地区河北医科大学第三医院药剂科河北省人民医院药学部河北医科大学第三医院中医科邢台市第三医院药剂科哈励逊国际和平医院药剂科

出处《中国医院用药评价与分析》 2023年第2期230-233,共4页 Evaluation and Analysis of Drug-use in Hospitals of China

基金河北省自然科学基金项目(No.H2021206407)。

关键词麝香保心丸复方丹参滴丸脑心通胶囊冠心病稳定型心绞痛 Shexiang Baoxin pills Compound Danshen dripping pills Naoxintong capsules Stable angina pectoris of coronary heart disease

分类号 R932 [医药卫生—生药学]