摘要
目的:评价正念干预对接受放疗和(或)化疗癌症病人焦虑、抑郁及疲乏水平的改善效果。方法:通过计算机检索PubMed、Web of Science、Cochrane、Embase、中国知网、万方、维普(VIP)、中国生物医学数据库中有关正念干预对放疗和(或)化疗癌症病人焦虑、抑郁及疲乏水平影响的随机对照试验,检索时间为建库至2022年5月。结果:共纳入15项随机对照试验。Meta分析结果显示,应用正念干预后接受放疗和(或)化疗的观察组病人的焦虑评分[SMD=-1.03,95%CI(-1.26,-0.81),P<0.00001]、抑郁评分[SMD=-1.25,95%CI(-1.67,-0.82),P<0.00001]和疲乏评分[SMD=-1.06,95%CI(-1.79,-0.33),P=0.005]均低于对照组,差异具有统计学意义。进一步亚组分析显示,接受正念干预的放化疗癌症病人焦虑、疲乏水平均未受不同干预时间及癌症类型的影响,抑郁水平的缓解因癌症类型不同出现差异。结论:正念干预可改善已完成或正在接受放疗和(或)化疗癌症病人的焦虑、抑郁及疲乏水平。
Objective:To evaluate the effect of mindfulness intervention on anxiety,depression and fatigue in cancer patients receiving radiotherapy and/or chemotherapy.Methods:PubMed,Web of Science,Cochrane,Embase,China National Knowledge Infrastructure(CNKI),Wanfang,VIP and China Biomedical Database were searched for randomized controlled trials on the effects of mindfulness intervention on anxiety,depression and fatigue in cancer patients undergoing radiotherapy and/or chemotherapy.The retrieval time was from the establishment of the database to May 2022.Results:A total of 15 randomized controlled trials were included in this study.The results of meta-analysis showed that after the mindfulness intervention,chemotherapy and/or radiotherapy of intervention group patients′anxiety score[SMD=-1.03,95%CI(-1.26,-0.81),P<0.00001],depression score[SMD=-1.25,95%CI(-1.67,-0.82),P<0.00001]and fatigue rating[SMD=-1.06,95%CI(-1.79,-0.33),P=0.005]were lower than those of control group,and the difference was statistically significant.Further subgroup analysis showed that the levels of anxiety and fatigue of cancer patients receiving mindfulness intervention were not affected by different intervention time and cancer types,and the remission of depression level was different with different cancer types.Conclusions:Mindfulness intervention can improve the levels of anxiety,depression and fatigue in cancer patients who have completed or are receiving radiotherapy and/or chemotherapy.
作者
李萍
韩谭倩
张振龙
韩梅
LI Ping;HAN Tanqian;ZHANG Zhenlong;HAN Mei(School of Nursing,Shandong First Medical University/Shandong Academy of Medical Sciences,Shandong 271016 China)
出处
《全科护理》
2023年第7期874-880,共7页
Chinese General Practice Nursing
关键词
正念干预
癌症
化疗
放疗
焦虑
抑郁
疲乏
META分析
mindfulness intervention
cancer
chemotherapy
radiotherapy
anxiety
depression
fatigue
Meta-analysis
