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机械通气重症肺炎患儿并发闭塞性毛细支气管炎的影响因素分析

Analysis on the Influencing Factors of Severe Pneumonia Children with Mechanical Ventilation Complicated with Bronchiolitis Obliterans
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摘要 目的:探讨机械通气重症肺炎患儿并发闭塞性毛细支气管炎(BO)的影响因素。方法:选取2020年1月—2022年3月莆田市儿童医院收治的83例机械通气重症肺炎患儿。统计所有患儿BO发生情况,并进行分组。收集所有患儿的基线资料。分析BO发生情况及分组情况,对机械通气重症肺炎患儿并发BO进行单因素及多因素分析。结果:83例机械通气重症肺炎患儿并发BO 21例,占比为25.30%,纳入发生组,未并发BO 62例,纳入未发生组。发生组病初使用激素、营养不良占比均高于未发生组,机械通气时间、发病后就诊时间均长于未发生组(P<0.05)。经logistic回归分析结果显示,机械通气时间长、病初使用激素、发病后就诊时间长及营养不良均是机械通气重症肺炎患儿并发BO的影响因素(OR>1,P<0.05)。结论:机械通气重症肺炎患儿有并发BO的风险,机械通气时间长、病初使用激素、发病后就诊时间长及营养不良均是机械通气重症肺炎患儿并发BO的影响因素。 Objective: To investigate the influencing factors of severe pneumonia children with mechanical ventilation complicated with bronchiolitis obliterans(BO). Method: A total of 83 severe pneumonia children with mechanical ventilation admitted to Putian Children’s Hospital from January 2020 to March 2022 were selected. The occurrence situation of BO in all children was counted and they were grouped. Baseline data was collected in all children. The occurrence situation of BO and grouping situation were analyzed, and the univariate and multivariate analysis were performed for the severe pneumonia children with mechanical ventilation complicated with BO.Result: Among the 83 severe pneumonia children with mechanical ventilation, 21 cases complicated with BO, accounted for 25.30%,and they were included in the occurrence group, and 62 cases without complicating with BO were included in the non occurrence group.The proportions of hormone used at the beginning of disease and malnutrition in the occurrence group were higher than those in the non occurrence group, and the time of mechanical ventilation and the visit time after onset were longer than those in the non occurrence group(P<0.05). The results of logistic regression analysis showed that long time of mechanical ventilation, hormone used at the beginning of disease, long visit time after onset and malnutrition were the influencing factors of severe pneumonia children with mechanical ventilation complicated with BO(OR>1, P<0.05). Conclusion: There is risk of complicating with BO in severe pneumonia children with mechanical ventilation have the risk of complicating with BO. Long time of mechanical ventilation, hormone used at the beginning of disease, long visit time after onset and malnutrition are the influencing factors of severe pneumonia children with mechanical ventilation complicated with BO.
作者 洪霜花 林丽钦 吴琳 HONG Shuanghua;LIN Liqin;WU Lin(Putian Children's Hospital,Putian 351100,China;不详)
机构地区 莆田市儿童医院
出处 《中外医学研究》 2023年第4期143-146,共4页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 重症肺炎 机械通气 闭塞性毛细支气管炎 影响因素 Severe pneumonia Mechanical ventilation Bronchiolitis obliterans Influencing factors
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