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剪切波弹性成像检测屈光近视患者眼球壁及眼周组织弹性的临床研究

Clinical study of shear wave elastography in detecting the elasticity of ocular wall and periocular tissue in patients with refractive myopia
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摘要 目的应用剪切波弹性成像(SWE)检测屈光近视患者眼球壁及眼周组织弹性,并评价测量结果的可重复性。方法选取我院健康志愿者33例(健康对照组)和屈光近视患者52例(屈光近视组),由2名检查者应用SWE测量球后壁视网膜-脉络膜-巩膜复合体、视神经、球后脂肪垫、内直肌、外直肌杨氏模量均值(Emean值),评价组间(不同检查者同日)测量的重复性;由同一检查者于同日上、下午及1周后重复测量眼部弹性参数,评价组内(同一检查者不同时间)测量的重复性。结果屈光近视组球后壁视网膜-脉络膜-巩膜复合体Emean值低于健康对照组,差异有统计学意义(P<0.05);两组视神经、球后脂肪垫、内直肌、外直肌Emean值比较差异均无统计学意义。重复性检验结果显示:(1)不同检查者同日所测Emean值比较差异均无统计学意义,ICC分别为0.71、0.75、0.79、0.73、0.75;(2)同一检查者同日2次所测Emean值比较差异均无统计学意义,球后壁视网膜-脉络膜-巩膜复合体、视神经、球后脂肪垫、内直肌、外直肌Emean值的组内相关系数(ICC)分别为0.82、0.85、0.86、0.83、0.84;(3)同一检查者一周2次所测Emean值比较差异均无统计学意义,球后壁视网膜-脉络膜-巩膜复合体、视神经、球后脂肪垫、内直肌、外直肌Emean值的ICC分别为0.79、0.82、0.82、0.80、0.78。Blant-Altman分析显示组内及组间所测Emean值均具有良好一致性。结论SWE可定量检查屈光近视患者眼球壁及眼周组织弹性,且其重复性较好。 Objective To assess the repeatability of shear wave elastography(SWE)in evaluating ocular andperiocular tissues in patients with refractive myopia.Methods A total of 33 healthy volunteers(healthy control group)and 52 refractive myopia patients(myopia group)were selected.The mean Young’s modulus(Emean value)of the retinal choroidalsclera complex,optic nerve,retrobulbar fat pad,internal rectus and external rectus of the posterior bulbar wall were measured bytwo examiners using SWE for evaluating the repeatability of measurement between examiners(different examiners on the sameday).The eye elastic parameters were repeatedly measured by the same examiner in the morning and afternoon on the same dayand 1 week later,the repeatability of measurement within the examiners(the same examiner at different times)was evaluated.Results The Emean values of the retina-choroid-sclera complex in the myopia group was lower than that in the healthycontrol group,and the difference was statistically significant(P<0.05).There were no statistically significant difference in theEmean values of the optic nerve,retrobulbar fat pad,internal rectus and external rectus between the two groups.Repeatability testresults were as followed:(1)Paired test showed no significant difference between the two measured values made by differentinspectors,the intra-class correlation coefficient ICC values of retina-choroid-sclera complex,optic nerve,retrobulbar fat tissue,Internal rectus muscle and external rectus muscle were 0.71,0.75,0.79,0.73,0.75,respectively.(2)Paired test showed no significant difference between the two measured values made by same inspectors on the same day.The intra-class correlationcoefficient(ICC)values of the retina-choroid-sclera complex,optic nerve,retrobulbar fat tissue,internal rectus muscle,and externalrectus muscle were 0.82,0.85,0.86,0.83,0.84,respectively.(3)Paired test showed no significant difference between the two measuredvalues made by same inspectors on the different days,the intra-class ICC values of retina-choroid
作者 李芳 吴蓉 陈静 姚明华 马骥 张志华 LI Fang;WU Rong;CHEN Jing;YAO Minghua;MA Ji;ZHANG Zhihua(Department of Ultrasoud,Shanghai General Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200080,China)
出处 《临床超声医学杂志》 CSCD 2023年第2期116-120,共5页 Journal of Clinical Ultrasound in Medicine
关键词 超声检查 剪切波弹性成像 眼部组织 眼周组织 重复性 Ultrasonography Shear wave elastography Ocular tissue Periocular tissue Repeatability
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