摘要
目的分析儿童不完全川崎病(IKD)的临床特征。方法收集2015年6月至2020年12月于福建省立金山医院住院的84例川崎病患儿的临床资料,按照诊断标准分为IKD组(n=37)与完全川崎病(CKD)组(n=47)。对两组患儿的临床资料,包括一般情况(性别、年龄)、临床表现(症状、体征)、辅助检查结果进行回顾性对照分析。结果IKD组的卡疤红肿发生率高于CKD组,差异有统计学意义(P<0.05)。IKD组皮疹、结膜充血、口唇改变、手足改变、非化脓性淋巴结肿大的发生率低于CKD组,差异有统计学意义(P<0.05)。两组患儿的肛周皮肤改变发生率比较,差异无统计学意义(P>0.05)。两组患儿的白细胞计数(WBC)、中性粒细胞比率、C反应蛋白(CRP)、降钙素原(PCT)、B型钠尿肽均值比较,差异无统计学意义(P>0.05)。两组患儿无菌性白细胞尿、肝功能异常、冠脉损伤发生率比较,差异无统计学意义(P>0.05)。结论IKD临床表现不典型,卡疤红肿在IKD诊断中具有重要价值。IKD可并发冠脉损伤,需及时诊断治疗。
Objective To analyze the clinical characteristics of incomplete Kawasaki disease(IKD)in children.Methods The clinical data of 84 children with Kawasaki disease hospitalized in Fujian Provincial Jinshan Hospital from June 2015 to December 2020 were collected.According to the diagnostic criteria,the children were divided into IKD group(n=37)and complete Kawasaki disease(CKD)group(n=47).The clinical data,including general conditions(gender,age),clinical manifestations(symptoms,signs)and auxiliary examination results were analyzed retrospectively.Results The incidence of scar swelling in IKD group was higher than that in CKD group,and the difference was statistically significant(P<0.05).The incidences of rash,conjunctival hyperemia,mouth and lip changes,hands and feet changes and non-suppurative lymphadenopathy in IKD group were lower than those in CKD group,and the differences were statistically significant(P<0.05).There was no significant difference in the incident of perianal skin changes between the two groups(P>0.05).There were no significant differences in the mean values of white blood cell count(WBC),neutrophil ratio,C-reactive protein(CRP)and prcalcitonin(PCT)and B-type natriuretic peptide(BNP)between the two groups(P>0.05).There were no significant differences in the incidents of aseptic leukocyturia,abnormal liver function and coronary artery injury between the two groups(P>0.05).Conclusion The clinical manifestations of IKD are atypical,and scar swelling is of great value in the diagnosis of IKD.IKD can also be complicated with coronary artery injury,which should be diagnosed and treated in time.
作者
王巧红
WANG Qiaohong(Department of Pediatrics,Fujian Provincial Jinshan Hospital,Fujian Provincial Hospital South Branch,Fujian Province,Fuzhou 350007,China)
出处
《中国当代医药》
CAS
2023年第6期88-91,95,共5页
China Modern Medicine
关键词
不完全川崎病
完全川崎病
临床特征
冠脉损伤
Incomplete Kawasaki disease
Complete Kawasaki disease
Clinical characteristics
Coronary artery injury
