摘要
目的 研究不同喂养方式对早产儿脑损伤患儿的肝肾功能、神经心理发育及预后的影响。方法 回顾性分析宝鸡市妇幼保健院2018年2月至2021年2月收治的750例早产儿脑损伤患儿的临床资料,按照喂养方式的不同分为三组各250例。A组患儿给予定量肠外营养支持,B组患儿给予母乳喂养,C组患儿给予配方奶营养支持。营养支持6个月后,比较三组患儿的发育指数(MDI)和运动发育指数(PDI);发育商(DQ)及Gesell发育量表评分情况;尿素氮(BUN)、肌酐(Cr)、谷氨酰转肽酶(GGT)、谷丙转氨酶(ALT)水平;体质量增长速率、身长增长速率及头围增长速率;并发症发生情况。结果 营养支持6个月后,B组和C组患儿的MDI、PDI评分分别为(90.75±10.13)分、(89.29±12.13)分和(91.07±12.26)分、(90.23±11.89)分,明显高于A组的(80.72±12.19)分、(81.25±10.31)分,差异均具有统计学意义(P<0.05);B组和C组患儿的MDI、PDI评分比较差异均无统计学意义(P>0.05)。A组、B组和C组患儿在语言、大动作、适应性、精细运动、个人社交方面的测评结果比较差异均无统计学意义(P>0.05)。6个月后,三组患儿的BUN、Cr、GGT、ALT比较差异均无统计学意义(P>0.05)。C组患儿的体质量增长速率、身长增长速率、头围增长速率分别为(17.35±4.01) g/(kg·d)、(1.19±0.39) cm/周、(0.84±0.17) cm/周,明显快于A组的(13.36±3.21) g/(kg·d)、(0.91±0.32) cm/周、(0.72±0.11) cm/周和B组的(13.99±3.97) g/(kg·d)、(0.92±0.32) cm/周、(0.72±0.11) cm/周,差异均有统计学意义(P<0.05);A组患儿的增长速率、身长增长速率、头围增长速率与B组比较差异无统计学意义(P>0.05)。三组患儿的并发症发生情况比较差异无统计学意义(P>0.05)。结论 配方奶喂养营养支持与肠外营养支持和母乳喂养比较能够有效帮助早产儿脑损伤患儿达到理想的营养状态,能够有效改善患儿的神经心理发育及预后,且对肝肾功能无明�
Objective To study the effects of different feeding methods on liver and kidney function, neuropsychological development, and prognosis of premature infants with brain injury. Methods A retrospective analysis was made on 750 cases of brain injury in premature infants admitted to Baoji Maternal and Child Health Hospital from February 2018 to February 2021. They were divided into three groups according to different feeding methods, with 250 cases in each group. Group A was given quantitative parenteral nutrition support, group B was given breast feeding, and group C was given formula for nutrition support. After 6 months of nutritional support, the development index(MDI) and motor development index(PDI) of three groups of preterm infants were compared. The development quotient(DQ) and Gesell development scale of three groups were compared. The levels of urea nitrogen(BUN), creatinine(CR), glutamyl transpeptidase(GGT), and alanine aminotransferase(ALT) were measured and compared among the three groups. The growth rate of body weight, body length, and head circumference were recorded and compared among the three groups.The complications of three groups of premature infants were compared. Results At the six-month follow-up, the MDI and PDI scores of preterm infants were(90.75±10.13) points,(89.29±12.13) points in group B,(91.07±12.26) points and(90.23 ± 11.89) points in group C, respectively, which were significantly higher than(80.72 ± 12.19) points and(81.25±10.31) points in group A(P<0.05). The MDI and PDI scores of preterm infants showed no statistically significant difference between group B and group C(P>0.05). The language, big action, fine action, social behavior, and cognitive ability in Gesell development scale showed no statistically significant difference among group A, group B, and group C(P>0.05). After 6 months of feeding, urea nitrogen(BUN), creatinine(Cr), glutamyl transpeptidase(GGT), and alanine aminotransferase(ALT) showed no statistically significant difference among the three groups(P>0.05)
作者
颉延卓
罗少龙
刘寅
JIE Yan-zhuo;LUO Shao-long;LIU Yin(Department of Child Health Care,Baoji Maternal and Child Health Hospital,Baoji 721000,Shaanxi,CHINA;Department of Neonatology,Baoji Maternal and Child Health Hospital,Baoji 721000,Shaanxi,CHINA)
出处
《海南医学》
CAS
2023年第4期537-540,共4页
Hainan Medical Journal
关键词
早产儿
脑损伤
不同喂养方式
肝肾功能
神经心理发育
预后
Premature infant
Brain damage
Different feeding methods
Liver and kidney function
Neuropsychological development
Prognosis
