摘要
目的探讨单孔胸腔镜在磨玻璃结节为主的早期肺癌手术切除中的应用效果。方法2015年1月~2021年3月收治的磨玻璃结节为主的早期肺癌病人168例均行手术切除。按照手术方法不同分为观察组和对照组,每组各84例,观察组实施单孔胸腔镜早期肺癌根治手术,对照组则实施传统三孔胸腔镜早期肺癌根治手术。比较两组病人术后1、3、5天疼痛情况、围手术期情况、手术前后炎性反应指标变化、手术前后生活质量及术后并发症发生率。结果观察组病人术后1天、3天、5天视觉模拟评分量表得分分别为(6.12±0.93)分、(5.12±0.73)分和(3.67±0.82)分,低于对照组的(6.53±0.91)分、(6.15±0.58)分和(4.36±0.91)分,差异有统计学意义(P<0.05)。观察组切口平均长度为(3.91±0.46)cm,引流管留置时间为(2.85±0.71)天,对照组分别为(6.63±0.86)cm和(3.69±0.87)天,两组比较差异有统计学意义(P<0.05)。观察组术后第5天C反应蛋白为(12.39±2.15)ng/L,降钙素原为(3.34±0.39)ng/ml、白细胞介素-6为(148.57±18.52)pg/ml,对照组分别为(24.09±3.41)ng/L、(4.78±0.51)ng/ml、(163.21±19.69)pg/ml,两组比较差异有统计学意义(P<0.05);观察组术后6个月肺癌病人生存质量测定量表为(108.41±4.26)分,高于对照组的(103.26±3.54)分,差异有统计学意义(P<0.05)。观察组并发症发生率为17.86%,对照组为22.62%,两组比较差异无统计学意义(P>0.05)。结论以磨玻璃结节为主的早期肺癌病人行单孔胸腔镜根治术,可降低创伤,减轻术后炎症反应,促进术后康复。
Objective To investigate the effect of single-hole thoracoscopy in the operation resection of early lung cancer with ground-glass nodules.Methods A total of 168 patients with early lung cancer mainly represented by ground-glass nodules who received surgical resection in our hospital from January 2015 to March 2021 were selected and divided into 2 groups according to different surgical methods.The observation group included 84 invalids were received single-hole thoracoscopic radical resection of early lung cancer,while the control group included 84 invalids were received traditional three-hole thoracoscopic radical resection.The pain,perioperative conditions,changes of inflammatory reaction indexes before and after operation,quality of life before and after surgery and the incidence of complications were compared between 2 groups.Results The visual analogue scale scores of(6.12±0.93)points,(5.12±0.73)points and(3.67±0.82)points in the observation group were lower than those of(6.53±0.91)points,(6.15±0.58)points and(4.36±0.91)points in the control group at 1 day,3 days and 5 days after operation(P<0.05).The average incision length of(3.91±0.46)cm and drainage tube indwelling time of(2.85±0.71)d in the observation group were shorter than those of(6.63±0.86)cm and(3.69±0.87)d in the control group(P<0.05).C-reactive protein(12.39±2.15)ng/L,procalcitonin(3.34±0.39)ng/ml and interleukin-6(148.57±18.52)pg/ml in the observation group were lower than those in the control group(24.09±3.41)ng/L,(4.78±0.51)ng/ml and(163.21±19.69)pg/ml at 5 days after operation(P<0.05).The quality of life scale of lung cancer patients in the observation group(108.41±4.26)was higher than that in the control group(103.26±3.54)at 6 months after operation(P<0.05).The incidence rate of complications in the observation group(17.86%)was not statistically significant compared with 22.62%in the control group(P>0.05).Conclusion The implementation of single hole thoracoscopic radical surgery for early lung cancer patients with ground gl
作者
吴智明
蒋磊
叶晟劼
赵文宇
WU Zhiming;JIANG Lei;YE Shengjie(Department of Cardio-Thoracic Surgery,Yixing Traditional Chinese Medicine Hospital,Jiangsu,Yixing 214200,China)
出处
《临床外科杂志》
2023年第1期53-56,共4页
Journal of Clinical Surgery
关键词
单孔胸腔镜
磨玻璃结节
肺癌
早期手术切除
single port thoracoscopy
ground glass nodules
lung cancer
surgical resection of early lung cancer
