摘要
目的 观察急性脑梗死(ACI)患者认知功能状况,分析ACI患者发生认知障碍(CI)的影响因素。方法 前瞻性纳入2019年10月至2021年10月汝州市第一人民医院收治的100例ACI患者,入院后对患者进行常规检查,详细记录患者的一般资料、实验室指标及影像学指标。治疗14 d时,应用蒙特利尔认知评估量表(MoCA)评估ACI患者CI发生情况,根据评估结果将患者分为CI组和认知功能正常组。经单因素、多因素分析ACI患者CI发生的影响因素。结果 100例ACI患者MoCA平均得分为(24.75±3.46)分;其中CI组46例(46.00%),认知功能正常组54例(54.00%)。单因素分析显示,合并糖尿病、吸烟史、同型半胱氨酸水平高、梗死部位为基底节是ACI患者发生CI的影响因素(P<0.05)。多因素分析显示,合并糖尿病、吸烟史、同型半胱氨酸水平高、梗死部位为基底节是ACI患者发生CI的危险因素(OR>1,P<0.05)。结论 ACI患者发生CI的影响因素为合并糖尿病、吸烟史、同型半胱氨酸水平高、梗死部位为基底节。
Objective To observe the cognitive function of patients with acute cerebral infarctionion(ACI) and analyze the influencing factor of cognitive impairment(CI) in ACI patients.Methods A total of 100 patients with ACI treated in the First People’s Hospital of Ruzhou from October 2019 to October 2021 were prospectively included. After admission, the patients were routinely examined, the general information, laboratory indicators and imaging indicators of the patients were recorded. At the 14th day of treatment, the incidence of CI in ACI patients was assessed with Montreal cognitive assessment(MoCA), and the patients were divided into CI group and normal cognitive function group according to the assessment results. The influencing factor of CI in ACI patients were analyzed by single factor and multi factor analysis.Results The mean MoCA score of 100 ACI patients was(24.75±3.46). There were 46 patients(46.00%) in CI group and 54 patients(54.00%) in normal cognitive function group. Univariate analysis showed that diabetes, smoking history, high level of homocysteine, and basal ganglia infarction were the influencing factor of CI in ACI patients(P<0.05). Multivariate analysis showed that the risk factors for CI in ACI patients were diabetes, smoking history, high level of homocysteine, and basal ganglia infarction(OR>1, P<0.05).Conclusion The influencing factor of CI in ACI patients were complicated with diabetes mellitus, smoking history, high homocysteine level and basal ganglia infarction.
作者
张亚萍
ZHANG Yaping(Department of Neurocritical Medicine,the First People’s Hospital of Ruzhou,Pingdingshan 467500,China)
出处
《河南医学研究》
CAS
2023年第3期467-470,共4页
Henan Medical Research
关键词
急性脑梗死
认知障碍
影响因素
acute cerebral infarctionion
cognitive impairment
influencing factor
