摘要
目的探究磁共振弥散加权成像(DWI-MRI)联合电子计算机断层(CT)增强扫描评估中央型肺癌患者放化疗效果的临床价值。方法选取76例接受放化疗治疗的中央型肺癌患者作为研究对象,治疗前后分别进行DWI-MRI、CT增强扫描,统计患者定量参数表观扩散系数(ADC)、不同部位中央肺癌情况,评估DWI-MRI、CT增强扫描对中央型肺癌患者放化疗效果的临床价值。结果放化疗前,CT增强扫描、DWI-MRI及二者联合检查的ADC差异无统计学意义(F=1.759,P=0.242);放化疗2、4、8周后,3种检查方法的ADC均高于放化疗前,CT增强扫描的ADC最低,差异均有统计学意义(P<0.05)。与DWI-MRI、CT增强扫描相比,二者联合检查肺门区肿块、纵膈淋巴结肿大、支气管腔内的检出率上升,差异有统计学意义(P<0.05)。ROC曲线表明,联合检查评估中央型肺癌放化疗效果的准确度(89.75%)高于CT增强扫描(82.35%)和DWI-MRI(79.36%)单项诊断,差异有统计学意义(P<0.05)。结论DWI-MRI联合CT增强扫描对中央型肺癌患者放化疗效果的评估价值较高,可为临床早期预防、治疗中央型肺癌提供资料依据。
Objective To explore the clinical value of magnetic resonance diffusion weighted imaging(DWI-MRI)combined with enhanced computed tomography(CT)in evaluating the effect of chemoradiotherapy in patients with central lung cancer.Methods Seventy-six patients with central lung cancer who received chemoradiotherapy were selected as the study object.DWI-MRI and enhanced CT scanning were performed before and after treatment,respectively.The patients’quantitative parameters,apparent diffusion coefficient(ADC),and the situation of central lung cancer in different parts were counted,and the clinical value of DWI-MRI and enhanced CT scanning in evaluating the effects of chemoradiotherapy on central lung cancer patients was evaluated.Results Before chemoradiotherapy,there was no significant difference in ADC between enhanced CT scanning,DWI-MRI,and their combined examinations(F=1.759,P=0.242).After 2,4,and 8 weeks of chemoradiotherapy,the ADC values of the three examination methods were higher than that before chemoradiotherapy,and the ADC of enhanced CT scanning was the lowest.The differences were statistically significant(P<0.05).Compared with DWI-MRI and enhanced CT scanning,the detection rate of hilar mass,mediastinal lymph node enlargement,and bronchial lumen in the combined examination of the two methods was significantly higher,and the difference was statistically significant(P<0.05).ROC curve showed that the accuracy of combined examination in evaluating the effect of chemoradiotherapy on central lung cancer(89.75%)was higher than that of enhanced CT scanning(82.35%)and DWI-MRI(79.36%)alone,and the differences were statistically significant(P<0.05).Conclusions DWI-MRI combined with enhanced CT scanning is of high value in evaluating the effect of chemoradiotherapy in patients with central lung cancer,and can provide data for early clinical prevention and treatment of central lung cancer.
作者
程维景
解礼冰
杜纯忠
CHENG Weijing;XIE Libing;DU Chunzhong(Radiology Department,The First People’s Hospital of Hangzhou Lin’an District,Hangzhou 311300,China)
出处
《健康研究》
CAS
2023年第1期99-102,108,共5页
Health Research
关键词
中央型肺癌
放化疗
磁共振弥散加权成像
电子计算机断层增强扫描
central lung cancer
chemoradiotherapy
magnetic resonance diffusion weighted imaging
computerized tomography enhanced scanning
