摘要
目的研究针刺结合盐酸阿芬太尼用于老年患者无痛肠镜检查中效果。方法选择于2019年3月—2020年6月在医院行无痛肠镜检查的老年患者78例作为研究对象,随机数字表法分为两组,各39例。对照组患者采用静脉输注丙泊酚麻醉,观察组患者联合盐酸阿芬太尼麻醉以及针刺治疗。数据观察:两组患者进镜成功率、麻醉优良率、麻醉效果指标(置镜检查时间及意识消失时间、恢复自主呼吸时间、睁眼时间、言语应答时间)、麻醉前及麻醉后两组患者血流动力学指标变化、麻醉时期炎症因子水平情况、麻醉疼痛分级情况、麻醉不良反应发生率、患者复查意愿率及肠镜检查满意率。结果两组患者进镜成功率均为100%(P>0.05);观察组患者麻醉优良率高于对照组患者(P<0.05);观察组患者麻醉效果,置镜检查时间及意识消失时间、恢复自主呼吸时间、睁眼时间、言语应答时间等指标均优于对照组患者(P<0.05);两组麻醉前血流动力学无统计学意义(P>0.05);两组麻醉后血流动力学水平均有所变化,观察组患者麻醉期间舒张压(diastolicbloodpressure,DBP)、收缩压(systolicbloodpressure,SBP)及血氧饱和度(pulse oxygen saturation,SPO2)水平高于对照组患者(P<0.05);两组T0时间点炎性因子无统计意义(P>0.05);麻醉诱导后(T0)两组hs-CRP和TNF-α水平差异无统计学意义(P>0.05);观察组麻醉后超敏C反应蛋白(high sensitive C-reactive protein,hs-CRP)、肿瘤坏死因子(tumor necrosis factor-α,TNF-α)水平在T1、T2、T3时间段均低于对照组(P<0.05);观察组患者麻醉疼痛分级情况优于对照组(P<0.05);观察组患者麻醉不良反应发生率低于对照组患者(P<0.05);观察组患者复查意愿率及肠镜检查满意率均高于对照组患者(P<0.05)。结论针刺结合盐酸阿芬太尼用于老年患者无痛肠镜检查中效果良好,患者麻醉效果佳,麻醉后恢复好,且炎症因子水平较低,对患者血流�
Objective To study the effect of acupuncture combined with alfentanil hydrochloride on painless colonoscopy in elderly patients.Methods Seventy-eight elderly patients who underwent painless colonoscopy in the hospital from March 2019 to June 2020 were selected as the study subjects,and were divided into two groups by random number table method,with 39 cases in each group.The control group was anesthetized with intravenous infusion of propofol,and the observation group was anesthetized with alfentanil hydrochloride and acupuncture.Data observation:the success rate of the two groups,the excellent and good rates of anesthesia,the indicators of anesthesia effect(the time of placing the mirror and the time of losing consciousness,the time of resuming spontaneous respiration,the time of opening the eyes,and the time of speech response),the changes of hemodynamic indicators of the two groups before and after anesthesia,the levels of inflammatory factors during anesthesia,the classification of anesthesia pain,the incidence of adverse effects of anesthesia,the rate of patients’willingness to review and the satisfaction rate of colonoscopy were compared.Results The success rate of endoscopy in both groups was 100%(P>0.05).The excellent and good rates of anesthesia in the observation group were higher than those of the control group(P<0.05).The anesthetic effect of the observation group,the time of endoscopy,the time of consciousness disappearance,the time to recover spontaneous breathing,the time to open eyes,the time to respond to speech and other indicators were better than those of the control group(P<0.05).There was no statistical significance in hemodynamics before anesthesia between the two groups(P>0.05).Hemodynamic levels in both groups were changed after anesthesia.The levels of diastolic blood pressure(DBP),systolic blood pressure(SBP)and blood oxygen saturation(SPO2)were higher than those of the control group(P<0.05).There was no statistical significance in inflammatory factors at T0 time point between the two
作者
李燕
郝巍
刘凤飞
张春雷
肖敬
刘婵
周娜
LI Yan;HAO Wei;LIU Fengfei;ZHANG Chunlei;XIAO Jing;LIU Chan;ZHOU Na(Hebei Hospital of Traditional Chinese Medicine,Shijiazhuang 050000,Hebei,China;Department of Oncology,The Seventh Peoples Hospital of Hebei Province,Dingzhou 073000,Hebei,China)
出处
《中华中医药学刊》
CAS
北大核心
2023年第1期255-258,共4页
Chinese Archives of Traditional Chinese Medicine
基金
河北省中医药管理局科研计划项目(2020011)。
关键词
针刺
盐酸阿芬太尼
老年患者
无痛肠镜检查
麻醉效果
麻醉不良反应率
acupuncture
alfentanil hydrochloride
elderly patients
painless colonoscopy
anesthetic effect
rate of adverse reaction to anesthesia
