摘要
癌症作为严重威胁人类健康的主要致死疾病之一,其负担之重亟待缓解,而卫生技术评估可为癌症的诊治防护及相关政策制定提供科学循证依据。成本-效用分析是卫生技术评估中经济学评价的金标准,而健康效用能否准确测量是决定其结果准确程度的关键要素之一。本文重点对癌症领域健康效用测量中的直接测量法、多属性健康效用测量量表法和映射法进行系统介绍并对其在癌症患者中的应用进行评述。其中,直接测量方法在癌症患者测量中存在操作复杂、成本较高以及对受试者的认知要求较高等不足;多属性健康效用测量量表法是当前癌症患者健康效用测量的首选方法;而映射法随着多属性健康效用测量量表中疾病特异性效用量表的不断发展完善,在未来应用中可能会逐渐减少。本文可为癌症领域卫生技术评估健康效用测量工具的选择提供参考,为优化癌症领域资源配置以及政策制定提供循证依据。
Cancer is one of the major fatal diseases that seriously threaten human health,and its burden needs to be solved urgently.Health technology assessment(HTA)can provide scientific evidence-based basis for cancer diagnosis,treatment,prevention and related policy formulation.Cost-utility analysis is the gold standard for economic evaluation in HTA,and the accurate measurement of its health utility is one of the key elements to determine the accuracy of its results.This article focuses on systematic introduction of direct measures,multi-attribute health utility scales,and mapping methods in the field of cancer measurement and reviews their applications in cancer patients.Among them,direct measures are complex,costly,and require a high level of subject knowledge;multi-attribute health utility measures are currently the preferred method for measuring health utility in cancer patients;with the continuous development and refinement of disease-specific utility measures in multi-attribute health utility instruments,the mapping method may gradually decrease in future applications.This paper can provide a reference for the selection of health utility measurement tools for HTA in the field of cancer,and provide evidence-based basis for optimizing resource allocation and policy formulation in the field of cancer.
作者
刘博
徐娟
Georg Kemmler
李浩飞
常恩雪
郑万基
谷文
周澜
刘瑞
黄卫东
罗南
LIU Bo;XU Juan;Georg Kemmler;LI Haofei;CHANG Enxue;ZHENG Wanji;GU Wen;ZHOU Lan;LIU Rui;HUANG Weidong;LUO Nan(School of Health Management,Harbin Medical University,Harbin 150081,China;Dept.for Psychiatry and Psychotherapy,Medical University of Innsbruck,Austria Innsbruck 6020,Austria;Saw Swee Hock School of Public Health,National University of Singapore,Singapore 117549,Singapore)
出处
《中国药房》
CAS
北大核心
2023年第4期450-456,共7页
China Pharmacy
基金
国家自然科学基金资助项目(No.71974048)
美国中华医学基金会公开竞争项目(No.CMB-19-308)。
关键词
癌症
健康效用
测量方法
卫生技术评估
成本-效用分析
cancer
health utility
measurement method
health technology assessment
cost-utility analysis
