摘要
目的探讨检测急诊脓毒血症患者降钙素原(PCT)的价值。方法选取医院2020年1月至2021年4月收治的急诊脓毒血症患者125例作为观察组,根据病情严重程度分为脓毒血症组、严重脓毒血症组、脓毒性休克组,分别为48例、46例、31例;选取同期的健康群体45人作为对照组,检测PCT水平,并进行组间比较。结果观察组患者的PCT水平显著高于对照组(P<0.05);观察组患者的3组间的PCT水平差异显著,且脓毒症组的PCT水平低于其余两组,脓毒性休克组最高(P<0.05);PCT水平与病情严重程度呈正相关关系(r=0.521,P<0.001);生存患者的PCT水平较死亡患者更低(P<0.05)。结论PCT水平检测对脓毒症患者的意义重大,对于评估病情严重程度及预后具有指导意义。
Objective To investigate the value of procalcitonin(PCT)detection in emergency patients with sepsis.Methods A total of 125 patients with acute sepsis admitted to the hospital from January 2020 to April 2021 were selected as the observation group.They were divided into the sepsis group(48 cases),the severe sepsis group(46 cases)and the septic shock group(31 cases)according to the severity of the disease.Forty-five healthy people in the same period were selected as the control group.The PCT level was detected in the observation group and the control group,and the difference was compared between groups.Results The PCT level in the observation group was significantly higher than that in the control group(P<0.05).The PCT level in the sepsis group,the severe sepsis group and the septic shock group was significantly different,that in the sepsis group was lower than that in the other two groups,and that in the septic shock group was the highest(P<0.05).The PCT level was positively correlated with the severity of the disease(r=0.521,P<0.001).The PCT level of living patients was lower than that of dead patients(P<0.05).Conclusion The detection of PCT level is of great significance for patients with sepsis,which has guiding significance for evaluating the severity of the disease and prognosis.
作者
程伟
翟炜
CHENG Wei;ZHAI Wei(The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang,Guizhou,China 550001)
出处
《中国药业》
CAS
2022年第S02期128-130,共3页
China Pharmaceuticals
基金
贵阳市科技计划项目[筑科合同2020-16-6]
贵州中医药管理局项目[QZYYXG-2020-3]。
