摘要
目的探讨布地奈德沙丁胺醇联合异丙托溴铵治疗支气管哮喘急性发作的临床疗效。方法选取医院2018年4月1日至2021年3月30日收治的支气管哮喘急性发作患者92例,按随机数字表法分为对照组和观察组,各56例。对照组患者给予布地奈德沙丁胺醇,观察组患者在对照组治疗基础上增加异丙托溴铵,比较两组的临床疗效。结果观察组患者治疗后的症状缓解时间、住院时间均显著短于对照组(P<0.05);观察组患者的肺功能、动脉血气水平等指标改善情况均显著好于对照组(P<0.05);观察组患者的并发症发生率显著低于对照组(P<0.05);两组患者的药品不良反应发生率无显著差异(P>0.05)。结论布地奈德沙丁胺醇联合雾化吸入异丙托溴铵治疗支气管哮喘急性发作的临床疗效显著,可快速缓解患者的疾病症状,改善其肺功能及组织器官氧气供给。
Objective To investigate the clinical efficacy of budesonide salbutamol combined with ipratropium bromide in the treatment of acute attack of bronchial asthma.Methods A total of 92 patients with acute attack of bronchial asthma admitted to the hospital from April 1,2018 to March 30,2021 were selected and divided into the control group and the observation group according to the random number table method,with 56 cases in each group.The patients in the control group were given budesonide salbutamol,on this basis,the patients in the observation group were given ipratropium bromide.The clinical efficacy in the two groups were compared.Results The symptom relief time and hospitalization time in the observation group were shorter than those in the control group(P<0.05).The improvement of pulmonary function and arterial blood gas level in the observation group was significantly better than that in the control group(P<0.05).The incidence of complications in the observation group was significantly lower than that in the control group(P<0.05).There was no significant difference in the incidence of adverse drug reactions between the two groups(P>0.05).Conclusion Budesonide salbutamol combined with aerosol inhalation of ipratropium bromide is effective in the treatment of patients witth acute attack of bronchial asthma is significant,which can rapidly relieve the symptoms of patients,improve their lung function and oxygen supply of tissues and organs.
作者
饶文明
谭清亚
RAO Wenming;TAN Qingya(Department of Respiratory and Critical Care Medicine,Kaizhou District People's Hospital,Chongqing,China 405400)
出处
《中国药业》
CAS
2022年第S02期65-67,共3页
China Pharmaceuticals
