摘要
目的:应用中医传承辅助系统(V3.0)分析贵州省将军山医院冠状病毒性肺炎患者的用药规律,为新冠肺炎的防治提供临床参考。方法:收集整理贵州省将军山医院2020年2月至2020年5月诊治新型冠状病毒肺炎中药处方197首,录入Excel 2019软件建立数据库,共涉及228味中药,应用中医传承辅助系统(V3.0)对其标准化录入、药物频次分析、药物四性五味分析、药物关联规则分析、药物类聚分析等,总结出贵州省将军山医院新冠肺炎患者的用药规律。结果:本次贵州省将军山医院治疗新冠肺炎的228味药,运用频次处于高位的中药依次为苍术、北沙参、贯众、玉竹、石斛、石菖蒲等;寒、温性药及辛、苦、甘味药频次较高;归肺、脾、胃经,功效属补虚、清热、化湿类;聚类分析得出5个核心方药组合。结论:分析发现贵州省将军山医院在治疗新冠肺炎多选用辛、苦、甘、寒、温性及归肺脾胃经的中药;其病机以“湿、热、寒、毒、瘀、虚”为特点,该病发展变化的核心则是“湿邪”为主;治则:急性期以祛湿解表、清热解毒为主,恢复期以养阴补虚为主。
Objective:To analyze the medication rules for patients with COVID-19 in Guizhou Jiangjunshan Hospital by using assistance system of Traditional Chinese Medicine inheritance(V3.0) to provide clinical reference for the prevention and treatment of COVID-19. Method: A total of 197 prescriptions of TCM for the diagnosis and treatment of COVID-19 in Guizhou Jiangjunshan Hospital from February 2020 to May 2020 were collected and input into Excel 2019 software to establish a database, involving a total of 228 traditional Chinese herbs. The assistance system TCM inheritance(V3.0) was used to standardize the entry, drug frequency analysis, drug four properties and five tastes analysis, drug association rule analysis, drug cluster analysis, etc., and the medication rules for COVID-19 patients in Guizhou Jiangjunshan Hospital were summarized. Results: Among the 228 herbs for treating COVID-19 in Guizhou Jiangjunshan Hospital, the most frequently used herbs were as follows: Atractylodes, North miltiorrhiza, Guanzhong, Yuzhu, Dendrobium, calamus, and etc,. Herbs with cold and warm nature, with acridity, bitter and sweet flavors were used more frequently. They belong to meridians of lung, spleen and stomach with the functions of tonifying deficiency, clearing heat and removing dampness. Based on cluster analysis, 5 core prescriptions were obtained. Conclusion: The analysis shows that in treating COVID-19 in Guizhou Jiangjunshan Hospital, herbs with flavors of acridity, bitter and sweet, with the nature of cold and warm, which belong to lung, spleen and stomach meridians, were used more. The pathogenesis of the disease is characterized by "dampness, heat, cold, poison, blood stasis and deficiency". The core of the development and change of the disease is "dampness evil". Treatment principles: in the acute stage, dispelling dampness and resolving the exterior, clearing heat and revolving toxin are the main treating methods, while in the rehabilitation stage, the method of nourishing Yin and supplementing deficiency is widely used
作者
余梅
李波
田杰
王帅
葛正行
肖政华
许滔
周洵
谭韬
杨义
杨晓燕
YU Mei;LI Bo;TIAN Jie;WANG Shuai;GE Zheng-xing;XIAO Zheng-hua;XU Tao;ZHOU Xun;TAN Tao;YANG Yi;YANG Xiao-yan(The Second Afiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550003,Guizhou,China;Guizhou University of Traditional Chinese Medicine,Guiyang 550025,Guizhou,China)
出处
《贵州中医药大学学报》
2023年第1期45-51,共7页
Journal of Guizhou University of Traditional Chinese Medicine
基金
2021年贵州省中医药管理局中医药防控新冠肺炎专项科研课题,项目编号:QZYYXG-2021-8。
