摘要
目的研究腔隙性脑梗死(LI)患者生态学执行功能损害的影响因素。方法纳入2019年1月至2021年1月南通大学附属南京江北医院收治的100例LI患者为对象作为正常观察组,另随机抽取100例同期体检健康人群作为正常对照组。统计两组年龄、性别、体质量指数(BMI)等一般资料,评估两组生态学执行功能评分,并采用多因素Logistic回归分析法分析LI患者生态学执行功能损害的独立影响因素。结果两组性别、BMI、吸烟史、饮酒史、糖尿病史、冠心病史、TC水平、TG水平、LDL水平、HDL水平比较差异无统计学意义(P>0.05),观察组年龄≥60岁、有高血压史、教育程度初中占比显著高于对照组(P<0.05)。观察组管理指数总分、元认知指数总分、BRIEF-A总分均显著高于对照组(P<0.05)。多因素Logistic回归分析显示,年龄≥60岁(OR=1.275、1.589、2.635,95%CI=1.071~1.518、1.258~2.007、1.852~3.749)、教育程度初中(OR=2.630、1.638、2.156,95%CI=1.260~5.490、1.271~2.111、1.368~3.398)、有高血压史(OR=4.058、5.635、2.736,95%CI=1.528~10.777、1.962~16.184、1.418~5.279)是管理指数总分、元认知指数总分、BRIEF-A总分的独立影响因素。结论LI患者生态学执行功能损害与年龄、教育程度、高血压病史密切相关。
Objective To study the influencing factors of ecological executive function damage in patients with lacunar infarction(LI).Methods 100 patients with LI treated in Nanjing Jiangbei Hospital Affiliated to Nantong University,from January 2019 to January 2021 were included as the normal observation group,and another 100 healthy people with physical examination during the same period were randomly selected as the normal control group.Collect two groups of general data such as age,gender,body mass index(BMI),evaluate the ecological executive function scores of the two groups,and use multivariate Logistic regression analysis to analyze the independent influencing factors of ecological executive function damage in patients with LI..Results There was no significant difference in gender,BMI,history of smoking,history of drinking,history of diabetes,history of coronary heart disease,TC level,TG level,LDL level,and HDL level between the two groups(P>0.05).The observation group was≥60 years old and had The proportion of high blood pressure history and education level in junior high school was significantly higher than that of the control group(P<0.05).The total score of management index,total score of metacognition index,and the total score of BRIEF-A of the observation group were significantly higher than those of the control group(P<0.05).Multivariate Logistic regression analysis showed that age≥60 years old(OR=1.275、1.589、2.635,95%CI=1.071~1.518、1.258~2.007、1.852~3.749),junior high school education(OR=2.630、1.638、2.156,95%CI=1.260~5.490、1.271~2.111、1.368~3.398),a history of hypertension(OR=4.058、5.635、2.736,95%CI=1.528~10.777、1.962~16.184、1.418~5.279)is the total score of the management index,The independent influencing factors of the total score of metacognition index and the total score of BRIEF-A.Conclusion The damage of ecological executive function in patients with LI is closely related to age,education level,and history of hypertension.
作者
卞伟伟
李奇
黄斌
Bian Weiwei;Li Qi;Huang Bin(Department of Neurology,Nanjing Jiangbei Hospital,Nantong University,Jiangsu 210000,China;不详)
出处
《脑与神经疾病杂志》
CAS
2022年第12期779-783,共5页
Journal of Brain and Nervous Diseases
关键词
腔隙性脑梗死
生态学执行功能
影响因素
Lacunar infarction
Ecological executive function
Influencing factors
