摘要
细菌感染目前仍是导致新生儿和5岁以下儿童死亡的重要病因,早期预测和诊断是改善预后亟待解决的临床问题。出生前或出生时细菌入侵所致的早期新生儿感染在其中占有很大比例,因临床表现隐匿、病情进展迅速,早期诊断困难。脐带血是胎儿血液循环的一部分,检测其中感染相关指标,理论上可以为预测和诊断早期新生儿细菌感染提供依据,但影响因素复杂多变。本文就脐血检测对早期新生儿细菌感染的预测和临床诊断价值进行综述。
Bacterial infectious disease is still an important cause of death of newborns and children under 5 years old. Early prediction and diagnosis are urgent clinical methods to improve prognosis. Early neonatal infection caused by bacterial invasion before and during birth accounts for a large proportion because of the hidden clinical manifestations, rapid progress of the disease, and poor early diagnosis. Detection of infection related indicators in umbilical cord blood, which is a part of fetal blood circulation, can theoretically provide evidence for the prediction and diagnosis of early neonatal bacterial infection. This paper reviews the recent research progress of umbilical cord blood detection in the prediction and diagnosis of early neonatal bacterial infection.
作者
徐灵敏
李诗宇
杨胤颖
杨欣鑫
XU Ling-min;LI Shi-yu;YANG Yin-ying;YANG Xin-xin(Qingpu Branch of Zhongshan Hospital,Fudan University,Shanghai 201700,China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2022年第24期3831-3835,共5页
Chinese Journal of Nosocomiology
基金
上海市卫生和计划生育委员会面上基金资助项目(201640081)
上海市科学技术委员会引导类基金资助项目(16411972500)。
关键词
脐血检测
早期新生儿
细菌感染
血细胞计数
炎症介质
诊断
Umbilical cord blood detection
Early neonates
Bacterial infection
Blood cell count
Inflammatory mediators
Diagnosis
