摘要
目的了解多部门合作实行闭环式管理对多药耐药菌医院感染的预防控制效果,以降低医院感染发病率。方法全院施行多药耐药菌目标性监测,对预警的患者多部门根据职责分工采取干预措施。2018-2020年医院检出的多药耐药菌分别为耐碳青霉烯大肠埃希菌(CR-Eco)、耐碳青霉烯肺炎克雷伯菌(CR-KP)、耐碳青霉烯铜绿假单胞菌(CR-PA)、耐碳青霉烯鲍氏不动杆菌(CR-AB)、耐甲氧西林金黄色葡萄球菌(MRSA)、耐万古霉素肠球菌(VRE),对其进行数据统计,分析各类多药耐药菌检出率、医院感染率的变化趋势。采用SPSS 18.0软件进行统计分析。结果2018-2020年多药耐药菌医院感染率呈现逐年下降趋势(χ^(2)=89.998,P<0.05),其中CR-AB(χ^(2)=17.067,P<0.001)、CR-PA(χ^(2)=12.025,P<0.002)、CR-KP(χ^(2)=43.258,P<0.001)、CR-Eco(χ^(2)=109.126,P<0.001)医院感染率逐年下降,差异有统计学意义。CR-AB(χ^(2)=55.876,P<0.001)、CR-PA(χ^(2)=52.662,P<0.001)、VRE(χ^(2)=10.925,P<0.001)检出率呈逐年下降,差异有统计学意义。结论通过多药耐药菌医院感染目标性监测,指导医院构建多部门有效的多药耐药菌感染防控体系,可有效降低多药耐药菌医院感染的发生。
OBJECTIVE To understand the preventive and control effect of multi-department cooperative closed-loop management on multidrug resistant bacteria,so as to reduce the incidence of nosocomial infection.METHODS The target monitoring of multidrug resistance bacteria in the hospital was carried out,and the early warning patients were intervened by the departments according to the division of responsibilities.From 2018 to 2020,the multidrug-resistant bacteria detected in the hospital were carbapenem-resistant Escherichia coli(CR-Eco),carbapenem-resistant Klebsiella pneumoniae(CR-KP),carbapenem-resistant Pseudomonas aeruginosa(CR-PA),carbapenem-resistant Acinetobacter baumannii(CR-AB),methicillin-resistant Staphylococcus aureus(MRSA)and Vancomycin-resistant Enterococci(VRE)were used to analyze the variation trends of detection rate and nosocomial infection rate.SPSS 18.0 software was used for statistical analysis.RESULTS From 2018 to 2020,the nosocomial infection rate of multidrug-resistant bacteria showed a downward trend year by year(χ^(2)=89.998,P<0.05).The nosocomial infection rates of CR-AB(χ^(2)=17.067,P<0.001),CE-PA(χ^(2)=12.025,P<0.002),CR-KP(χ^(2)=43.258,P<0.001)and CR-Eco(χ^(2)=109.126,P<0.001)decreased year by year,with significant differences.The detection rates of CR-AB(χ^(2)=55.876,P<0.001),CR-PA(χ^(2)=52.662,P<0.001)and VRE(χ^(2)=10.925,P<0.001)decreased year by year,and the difference was significant.CONCLUSION Through the targeted monitoring of multi-drug resistant bacteria nosocomial infection,guiding the hospital to build an effective multi department system for multi drug resistant bacteria infection prevention and control can effectively reduce the incidence of multi drug resistant bacteria nosocomial infection.
作者
徐朋
吕玉玲
迟苗苗
唐琳娜
王洋
赵丽香
赵方
王丽丽
XU Peng;LYU Yu-ling;CHI Miao-miao;TANG Lin-na;WANG Yang;ZHAO Li-xiang;ZHAO Fang;WANG Li-li(The First Affiliated Hospital of Shandong First Medical University,Jinan,Shandong 250014,China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2022年第24期3779-3782,共4页
Chinese Journal of Nosocomiology
基金
山东省医药卫生科技发展基金资助项目(2018WS099)
中国老年医学学会感染防控研究基金资助项目(GRYJ-KLB2018026)。
关键词
多药耐药菌
目标性监测
闭环式管理
感染率
感染控制
Multidrug resistant bacteria
Target surveillance
Closed-loop management
Infection rate
Infection control
